Tissue factor in COVID-19-associated coagulopathy

S Subramaniam, H Kothari, M Bosmann - Thrombosis Research, 2022 - Elsevier
Evidence of micro-and macro-thrombi in the arteries and veins of critically ill COVID-19
patients and in autopsies highlight the occurrence of COVID-19-associated coagulopathy …

The complement system: A key player in the host response to infections

A Jayaraman, S Walachowski… - European Journal of …, 2024 - Wiley Online Library
Infections are one of the most significant healthcare and economic burdens across the world
as underscored by the recent coronavirus pandemic. Moreover, with the increasing …

Aging is associated with an insufficient early inflammatory response of lung endothelial cells in SARS-CoV-2 infection

S Subramaniam, D Kenney, A Jayaraman… - Frontiers in …, 2024 - frontiersin.org
Advanced age is associated with an increased susceptibility to Coronavirus Disease
(COVID)-19 and more severe outcomes, although the underlying mechanisms are …

Does SARS-CoV-2 infect platelets?

S Subramaniam, N Mohiuddin, A Jose - Frontiers in Immunology, 2024 - frontiersin.org
COVID-19 is characterized by dysregulated thrombo-inflammatory responses and
coagulation, leading to an increased risk of mortality in affected patients (1–3). Platelets play …

Gene expression changes in COVID-19 patients impact pathways related to circadian rhythm, phosphatidylinositol signaling, cytokine storm, and platelet aggregation

S Modi, N Gandhi, H Yoon, J Kuack, H Jee, C Enwere… - Gene Reports, 2023 - Elsevier
The emergence of SARS-CoV-2 and the resulting COVID-19 disease pandemic had a grave
impact on human society causing severely ill patients were to be placed on mechanical …

Rise of the SARS-CoV-2 Variants: can proteomics be the silver bullet?

A Acharjee, J Stephen Kingsly, M Kamat… - Expert Review of …, 2022 - Taylor & Francis
Introduction The challenges posed by emergent strains of SARS-CoV-2 need to be tackled
by contemporary scientific approaches, with proteomics playing a significant role. Areas …