Cationic host defence peptides (CHDP), also known as antimicrobial peptides, are naturally
occurring peptides that can combat infections through their direct microbicidal properties …

Defensins are a major family of host defense peptides expressed predominantly in
neutrophils and epithelial cells. Their broad antimicrobial activities and multifaceted …

Interferon-induced transmembrane proteins (IFITMs) inhibit infection of diverse enveloped
viruses, including the influenza A virus (IAV) which is thought to enter from late endosomes …

Defensins are an effector component of the innate immune system with broad antimicrobial
activity. Humans express two types of defensins, α-and β-defensins, which have antiviral …

BACKGROUND Reproductive tract infection is an important factor leading to male and
female infertility. Among female infertility factors, microbial and viral infections are the main …

α, β, and θ defensins are effectors of the innate immune system with potent antibacterial,
antiviral, and antifungal activity. Defensins have direct antiviral activity in cell culture, with …

Infectious diseases caused by bacteria, viruses or fungi are among the leading causes of
death worldwide. The emergence of drug-resistance mechanisms, especially among …

Antimicrobial peptides (AMPs) are ubiquitously present small peptides, which play a critical
function in the innate immune system. The defensin class of AMPs represented an …

Peptides with broad-spectrum antimicrobial activity are found widely expressed throughout
nature. As they participate in a number of different aspects of innate immunity in mammals …

There is a pressing need to develop new antiviral treatments; of the 60 drugs currently
available, half are aimed at HIV-1 and the remainder target only a further six viruses. This …