Allergic rhinitis (AR) is a global health problem that causes major illnesses and disabilities
worldwide. Epidemiologic studies have demonstrated that the prevalence of AR has …

The small regulatory RNA microRNA-21 (miR-21) plays a crucial role in a plethora of
biological functions and diseases including development, cancer, cardiovascular diseases …

The pathogenesis of allergic rhinitis is associated with genetic, environmental, and
epigenetic factors. Genotyping of single nucleotide polymorphisms (SNPs) is an advanced …

MicroRNAs (miRNAs) are small non-coding RNA molecules that are 18–22 nucleotides long
and highly conserved throughout evolution. Currently, they are considered one of the …

Allergic inflammation is accompanied by the coordinated expression of a myriad of genes
and proteins that initiate, sustain, and propagate immune responses and tissue remodeling …

Regulation of inflammatory responses is ensured by coordinated control of gene expression
in participating immune system and tissue cells. One group of gene expression regulators …

IL-4 was first identified as a T cell-derived growth factor for B cells. Studies over the past
several decades have markedly expanded our understanding of its cellular sources and …

MicroRNAs (miRNAs or miRs) are endogenous, small RNA molecules that suppress
expression of targeted mRNA. miR-21, one of the most extensively studied miRNAs, is …

MicroRNAs are being exploited for diagnosis, prognosis and monitoring of cancer and other
diseases. Their high tissue specificity and critical role in oncogenesis provide new …

An ECoScreen condenser (Jaeger) was used to collect samples over 20 minutes, 500 mL of
condensate was mixed with DNase to digest DNA, and then RNA was isolated with TRIzol …