The circadian clock is the biochemical oscillator with a near 24-h period that is responsible
for generating the circadian rhythms in peripheral organs including the lung. Mounting …

Disrupted daily or circadian rhythms of lung function and inflammatory responses are
common features of chronic airway diseases. At the molecular level these circadian rhythms …

Molecular clock REV-ERBα is central to regulating lung injuries, and decreased REV-ERBα
abundance mediates sensitivity to pro-fibrotic insults and exacerbates fibrotic progression. In …

Cigarette smoke (CS) is the main etiological factor in the pathogenesis of
emphysema/chronic obstructive pulmonary disease (COPD), which is associated with …

Cigarette smoke contains numerous chemical compounds, including abundant reactive
oxygen/nitrogen species and aldehydes, and many other carcinogens. Long-term cigarette …

Abstract Background/Aims: Chronic obstructive pulmonary disease (COPD) is a major cause
of morbidity and mortality worldwide. This study aimed to identify overlapping or diverging …

Maresin-1 is one of the representative specialized pro-resolving mediators that has shown
beneficial effects in inflammatory disease models. Recently, two distinct types of receptor …

The negative health effects of shift work, including carcinogenesis, may be mediated by
changes in DNA methylation, particularly in the circadian genes. Using the Infinium …

The function of the circadian cycle is to determine the natural 24 h biological rhythm, which
includes physiological, metabolic, and hormonal changes that occur daily in the body. This …

Chronic obstructive pulmonary disease (COPD) is the fourth most common cause of death,
and it is characterized by abnormal inflammation and lung function decline. Although the …