[HTML][HTML] Membrane mimetic-dependence of GPCR energy landscapes

N Thakur, AP Ray, B Jin, NP Afsharian, E Lyman… - Structure, 2024 - cell.com
We leveraged variable-temperature 19 F-NMR spectroscopy to compare the conformational
equilibria of the human A 2A adenosine receptor (A 2A AR), a class AG protein-coupled …

Human Cells for Human Proteins: Isotope Labeling in Mammalian Cells for Functional NMR Studies of Disease-Relevant Proteins

P Rößler, M Ruckstuhl, A Löbbert, T Stühlinger… - bioRxiv, 2024 - biorxiv.org
In biological and biomedical research the focus progressively moves towards difficult human
proteins, which often can only be expressed in higher eukaryotic cells. Nuclear magnetic …