Oral diseases, such as caries and periodontitis, not only have local effects on the dentition
and on tooth‐supporting tissues but also may impact a number of systemic conditions …

Periodontitis is a chronic inflammatory disease that causes damage to periodontal tissues,
which include the gingiva, periodontal ligament, and alveolar bone. The major cause of …

Background Macrophage M1 polarization plays a pivotal role in inflammatory diseases.
Progranulin (PGRN) has potential anti-inflammation action, however, the effect of PGRN on …

BACKGROUND: Chronic inflammation in periodontal disease has been suggested as a
potential risk factor in Alzheimer's disease (AD). The purpose of this study was to examine …

The ultimate goal of periodontal therapy is to prevent further attachment loss and predictably
restore the periodontal supporting structures that were lost because of disease or trauma in …

Background Two reports by the US surgeon general noted the disproportionate impact of
oral disease on and lack of oral health information regarding people with disabilities …

In the last 10 years, a rising number of epidemiological investigations have studied the
possible association between chronic oral infections and cardiovascular diseases (CVD) …

Objectives To determine whether there is an association between tooth loss, chewing ability,
and cognitive function in a general elderly population. Design Data from the P anel S tudy of …

Background: There has been an explosion in research into possible associations between
periodontitis and various systemic diseases and conditions. Aim: To review the evidence for …

Salivary biomarker discovery requires identification of analytes with high discriminatory
capacity to distinguish disease from health, including day-to-day variations that occur in …