Large-vessel vasculitis (LVV) manifests as inflammation of the aorta and its major branches
and is the most common primary vasculitis in adults. LVV comprises two distinct conditions …

Objectives Temporal artery biopsy (TAB) is a reference test for the diagnosis of GCA but
reveals inflammatory changes only in a subset of patients. The lack of knowledge of TAB …

Purpose Management of giant cell arteritis (GCA, Horton's disease) involves many
uncertainties. This work was undertaken to establish French recommendations for GCA …

Giant cell arteritis (GCA) is the most common type of primary vasculitis in Western countries.
Polymyalgia rheumatica (PMR) is the second most common inflammatory rheumatic disease …

Giant cell arteritis (GCA) is a common form of primary systemic vasculitis in adults, with no
reliable indicators of prognosis or treatment responses. We used single cell technologies to …

In recent years, the relationship between inflammation and thrombosis has been deeply
investigated and it is now clear that immune and coagulation systems are functionally …

Microvascular networks in the adventitia of large arteries control access of inflammatory cells
to the inner wall layers (media and intima) and thus protect the immune privilege of the aorta …

Vaccines are important for protecting individuals at increased risk of severe infections,
including patients undergoing DMARD therapy. However, DMARD therapy can also …

Abstract Pentraxin-3 (PTX3) is the prototype of the long pentraxin subfamily, an acute-phase
protein consisting of a C-terminal pentraxin domain and a unique N-terminal domain. PTX3 …

The term “vasculitis” refers to a group of rare immune‐mediated diseases characterized by
the dysregulated immune system attacking blood vessels located in any organ of the body …