Advances in the synthesis of β-alanine

P Song, X Zhang, S Wang, W Xu, F Wei - Frontiers in Bioengineering …, 2023 - frontiersin.org
β-Alanine is the only naturally occurring β-type amino acid in nature, and it is also one of the
very promising three-carbon platform compounds that can be applied in cosmetics and food …

Cell-free systems and genetic biosensors for accelerating enzyme and pathway prototyping

W Kim, S Lee, BH Sung, JG Na, JW Lee - Current Opinion in Systems …, 2024 - Elsevier
Integration of cell-free systems with genetic biosensors is emerging as an advantageous
platform for small molecule detection. This biosensor-coupled cell-free system simplifies an …

Additive Manufacturing of Engineered Living Materials with Bio‐Augmented Mechanical Properties and Resistance to Degradation

G Altin‐Yavuzarslan, SM Brooks… - Advanced functional …, 2023 - Wiley Online Library
Engineered living materials (ELMs) combine living cells with polymeric matrices to yield
unique materials with programmable functions. While the cellular platform and the polymer …

Selective 8-oxo-rG stalling occurs in the catalytic core of polynucleotide phosphorylase (PNPase) during degradation

LG Miller, W Kim, S Schowe, K Taylor, R Han… - Proceedings of the …, 2024 - pnas.org
RNA oxidation, predominantly through the accumulation of 8-oxo-7, 8-dihydroguanosine (8-
oxo-rG), represents an important biomarker for cellular oxidative stress. Polynucleotide …

Microbial chassis design and engineering for production of amino acids used in food industry

J Wang, W Ma, J Zhou, X Wang - Systems Microbiology and …, 2023 - Springer
Rational microbial chassis design and engineering for improving production of amino acids
have attracted a considerable attention. l-glutamate, l-lysine, l-threonine and l-tryptophan …

p-Nitrobenzoate production from glucose by utilizing p-aminobenzoate N-oxygenase: AurF

A Mori, Y Hirata, M Kishida, Y Mori, A Kondo… - Enzyme and Microbial …, 2023 - Elsevier
Nitroaromatic compounds are widely used in industry, but their production is associated with
issues such as the hazardousness of the process and low regioselectivity. Here, we …

Discovery and Engineering of a Novel Bacterial L-Aspartate α-Decarboxylase for Efficient Bioconversion

W Cui, H Liu, Y Ye, L Han, Z Zhou - Foods, 2023 - mdpi.com
L-aspartate α-decarboxylase (ADC) is a pyruvoyl-dependent decarboxylase that catalyzes
the conversion of L-aspartate to β-alanine in the pantothenate pathway. The enzyme has …

A self-stimulating system based on a polyhydroxyalkanoates coupled induction mechanism and its applications for Halomonas

S Zheng, Z Zhang, P Jiang, J Wang, Y Zheng… - Chemical Engineering …, 2024 - Elsevier
Inducible gene expression systems are vital tools for synthetic biology. This study focused
on a microbial polyhydroxyalkanoate (PHA) related inducible expression system, namely …

[HTML][HTML] Metabolic and enzymatic engineering approach for the production of 2-phenylethanol in engineered Escherichia coli

S Noda, Y Mori, Y Ogawa, R Fujiwara, M Dainin… - Bioresource …, 2024 - Elsevier
Phenylethanol, known for its rose-like odor and antibacterial activity, is synthesized via
exogenous phenylpyruvate by the sequential reaction of phenylpyruvate decarboxylase …

Metabolic engineering strategies for L-Homoserine production in Escherichia coli

X Jin, S Wang, Y Wang, Q Qi, Q Liang - Microbial Cell Factories, 2024 - Springer
L-Homoserine, serves as a non-essential precursor for the essential amino acids derived
from L-aspartate in both animals and humans. It finds widespread applications across the …