Antimicrobial peptides and proteins: From nature's reservoir to the laboratory and beyond

T Sarkar, M Chetia, S Chatterjee - Frontiers in Chemistry, 2021 - frontiersin.org
Rapid rise of antimicrobial resistance against conventional antimicrobials, resurgence of
multidrug resistant microbes and the slowdown in the development of new classes of …

Intracellular targeting mechanisms by antimicrobial peptides

CF Le, CM Fang, SD Sekaran - Antimicrobial agents and …, 2017 - Am Soc Microbiol
Antimicrobial peptides (AMPs) are expressed in various living organisms as first-line host
defenses against potential harmful encounters in their surroundings. AMPs are short …

[HTML][HTML] Antimicrobial peptides

L Zhang, RL Gallo - Current biology, 2016 - cell.com
Antimicrobial peptides and proteins (AMPs) are a diverse class of naturally occurring
molecules that are produced as a first line of defense by all multicellular organisms. These …

[HTML][HTML] The human cathelicidin LL-37—A pore-forming antibacterial peptide and host-cell modulator

D Xhindoli, S Pacor, M Benincasa, M Scocchi… - … et Biophysica Acta (BBA …, 2016 - Elsevier
The human cathelicidin hCAP18/LL-37 has become a paradigm for the pleiotropic roles of
peptides in host defence. It has a remarkably wide functional repertoire that includes direct …

Antimicrobial peptides of multicellular organisms

M Zasloff - nature, 2002 - nature.com
Multicellular organisms live, by and large, harmoniously with microbes. The cornea of the
eye of an animal is almost always free of signs of infection. The insect flourishes without …

Mode of action of membrane active antimicrobial peptides

Y Shai - Peptide Science: Original Research on Biomolecules, 2002 - Wiley Online Library
Water‐membrane soluble protein and peptide toxins are used in the defense and offense
systems of all organisms, including plants and humans. A major group includes …

[HTML][HTML] Studies on anticancer activities of antimicrobial peptides

DW Hoskin, A Ramamoorthy - Biochimica et Biophysica Acta (BBA) …, 2008 - Elsevier
In spite of great advances in cancer therapy, there is considerable current interest in
developing anticancer agents with a new mode of action because of the development of …

Granules of the human neutrophilic polymorphonuclear leukocyte

N Borregaard, JB Cowland - … Journal of the American Society of …, 1997 - ashpublications.org
Fig 2. Classification of granules in neutrophils. Peroxidase-positive (azurophilic or primary)
granules are characterized by the content of MPO and may be further divided based on their …

Antimicrobial peptides: premises and promises

KVR Reddy, RD Yedery, C Aranha - International journal of antimicrobial …, 2004 - Elsevier
Antimicrobial peptides (AMPs) are an important component of the natural defences of most
living organisms against invading pathogens. These are relatively small (< 10kDa), cationic …

The multifaceted roles of proline in cell behavior

EJ Patriarca, F Cermola, C D'Aniello, A Fico… - Frontiers in cell and …, 2021 - frontiersin.org
Herein, we review the multifaceted roles of proline in cell biology. This peculiar cyclic imino
acid is:(i) A main precursor of extracellular collagens (the most abundant human proteins) …