Enhancing precision in human neuroscience

S Nebe, M Reutter, DH Baker, J Bölte, G Domes… - Elife, 2023 - elifesciences.org
Human neuroscience has always been pushing the boundary of what is measurable. During
the last decade, concerns about statistical power and replicability–in science in general, but …

Current trends and opportunities in the methodology of electrodermal activity measurement

C Tronstad, M Amini, DR Bach… - Physiological …, 2022 - iopscience.iop.org
Electrodermal activity (EDA) has been measured in the laboratory since the late 1800s.
Although the influence of sudomotor nerve activity and the sympathetic nervous system on …

Quantifying model selection uncertainty via bootstrapping and Akaike weights

E Rigdon, M Sarstedt… - International Journal of …, 2023 - Wiley Online Library
Picking one 'winner'model for researching a certain phenomenon while discarding the rest
implies a confidence that may misrepresent the evidence. Multimodel inference allows …

Measuring learning in human classical threat conditioning: Translational, cognitive and methodological considerations

KE Ojala, DR Bach - Neuroscience & Biobehavioral Reviews, 2020 - Elsevier
Threat conditioning is a laboratory model of associative learning across species that is often
used in research on the etiology and treatment of anxiety disorders. At least 10 different …

Cross-species anxiety tests in psychiatry: pitfalls and promises

DR Bach - Molecular Psychiatry, 2022 - nature.com
Behavioural anxiety tests in non-human animals are used for anxiolytic drug discovery, and
to investigate the neurobiology of threat avoidance. Over the past decade, several of them …

[HTML][HTML] Psychophysiological modelling and the measurement of fear conditioning

DR Bach, F Melinscak - Behaviour research and therapy, 2020 - Elsevier
Quantification of fear conditioning is paramount to many clinical and translational studies on
aversive learning. Various measures of fear conditioning co-exist, including different …

Consensus design of a calibration experiment for human fear conditioning

DR Bach, J Sporrer, R Abend, T Beckers… - Neuroscience & …, 2023 - Elsevier
Fear conditioning is a widely used laboratory model to investigate learning, memory, and
psychopathology across species. The quantification of learning in this paradigm is …

Multiverse analyses in fear conditioning research

TB Lonsdorf, A Gerlicher, M Klingelhöfer-Jens… - … Research and Therapy, 2022 - Elsevier
There is heterogeneity in and a lack of consensus on the preferred statistical analyses in
light of a multitude of potentially equally justifiable approaches. Here, we introduce …

Robust group-but limited individual-level (longitudinal) reliability and insights into cross-phases response prediction of conditioned fear

M Klingelhöfer-Jens, MR Ehlers, M Kuhn, V Keyaniyan… - Elife, 2022 - elifesciences.org
Here, we follow the call to target measurement reliability as a key prerequisite for individual-
level predictions in translational neuroscience by investigating (1) longitudinal reliability at …

Navigating the manyverse of skin conductance response quantification approaches–A direct comparison of trough‐to‐peak, baseline correction, and model‐based …

M Kuhn, AMV Gerlicher, TB Lonsdorf - Psychophysiology, 2022 - Wiley Online Library
Raw data are typically required to be processed to be ready for statistical analyses, and
processing pipelines are often characterized by substantial heterogeneity. Here, we applied …