[HTML][HTML] Therapies to prevent post-infarction remodelling: From repair to regeneration

P Contessotto, A Pandit - Biomaterials, 2021 - Elsevier
Myocardial infarction is the first cause of worldwide mortality, with an increasing incidence
also reported in developing countries. Over the past decades, preclinical research and …

Exosome-bearing hydrogels and cardiac tissue regeneration

H Amini, AR Namjoo, MT Narmi, N Mardi… - Biomaterials …, 2023 - spj.science.org
Background In recent years, cardiovascular disease in particular myocardial infarction (MI)
has become the predominant cause of human disability and mortality in the clinical setting …

Interleukin-10 deficiency alters endothelial progenitor cell–derived exosome reparative effect on myocardial repair via integrin-linked kinase enrichment

Y Yue, C Wang, C Benedict, G Huang… - Circulation …, 2020 - Am Heart Assoc
Rationale: Systemic inflammation compromises the reparative properties of endothelial
progenitor cell (EPC) and their exosomes on myocardial repair, although the underlying …

Mesenchymal stem cell transplantation for ischemic diseases: mechanisms and challenges

TT Van Nguyen, NB Vu, P Van Pham - Tissue Engineering and …, 2021 - Springer
Ischemic diseases are conditions associated with the restriction or blockage of blood supply
to specific tissues. These conditions can cause moderate to severe complications in …

[HTML][HTML] Neovascularization: the main mechanism of MSCs in ischemic heart disease therapy

W Shi, Q Xin, R Yuan, Y Yuan, W Cong… - Frontiers in …, 2021 - frontiersin.org
Mesenchymal stem cell (MSC) transplantation after myocardial infarction (MI) has been
shown to effectively limit the infarct area in numerous clinical and preclinical studies …

[HTML][HTML] Mid-to long-term efficacy and safety of stem cell therapy for acute myocardial infarction: a systematic review and meta-analysis

H Lee, HJ Cho, Y Han, SH Lee - Stem Cell Research & Therapy, 2024 - Springer
Background This comprehensive systematic review and meta-analysis investigated the mid-
to long-term efficacy and safety of stem cell therapy in patients with acute myocardial …

[HTML][HTML] Unlocking the pragmatic potential of regenerative therapies in heart failure with next-generation treatments

Y Kishino, K Fukuda - Biomedicines, 2023 - mdpi.com
Patients with chronic heart failure (HF) have a poor prognosis due to irreversible impairment
of left ventricular function, with 5-year survival rates< 60%. Despite advances in …

[HTML][HTML] Intramyocardial stem cell transplantation during coronary artery bypass surgery safely improves cardiac function: meta-analysis of 20 randomized clinical trials

TW Soetisna, AMH Thamrin, D Permadijana… - Journal of Clinical …, 2023 - mdpi.com
IMSC transplantation during CABG is considered one of the most promising methods to
effectively deliver stem cells and has been widely studied in many trials. But the results of …

Diabetes impairs cardioprotective function of endothelial progenitor cell-derived extracellular vesicles via H3K9Ac inhibition

G Huang, Z Cheng, A Hildebrand… - Faculty …, 2022 - scholarshare.temple.edu
Background and Purpose: Myocardial infarction (MI) in diabetic patients results in higher
mortality and morbidity. We and others have previously shown that bone marrow-endothelial …

Adipose-derived stem cells for regenerative wound healing applications: understanding the clinical and regulatory environment

J Luck, BD Weil, M Lowdell… - Aesthetic surgery …, 2020 - academic.oup.com
There is growing interest in the regenerative potential of adipose-derived stem cells
(ADSCs) for wound healing applications. ADSCs have been shown to promote …