The effective size of a population, N e, determines the rate of change in the composition of a
population caused by genetic drift, which is the random sampling of genetic variants in a …

Population‐genetic studies have been remarkably productive and successful in the last
decade following the invention of PCR technology and the introduction of mitochondrial and …

Sexual reproduction is a fundamental aspect of life. It is defined by the occurrence of meiosis
and the fusion of two gametes of different sexes or mating types. Sex-determination …

Positive selection can be inferred from its effect on linked neutral variation. In the restrictive
case when there is no recombination, all linked variation is removed. If recombination is …

A major goal in human genetics is to understand the role of common genetic variants in
susceptibility to common diseases. This will require characterizing the nature of gene …

We employed deep genome sequencing of two parents and 12 of their offspring to estimate
the mutation rate per site per generation in a full-sib family of Drosophila melanogaster …

The population genetic perspective is that the processes shaping genomic variation can be
revealed only through simultaneous investigation of sequence polymorphism and …

In many species, sex is determined by a system based on X and Y chromosomes, the latter
having lost much of their genetic activity. Y chromosomes have evolved independently many …

The hypothesis that ornaments can honestly signal quality only if their expression is
condition-dependent has dominated the study of the evolution and function of colour traits …

This report of independent genome sequences of two natural populations of Drosophila
melanogaster (37 from North America and 6 from Africa) provides unique insight into forces …