High content design of riboswitch biosensors: All-around rational module-by-module design

Y Wu, L Zhu, S Li, H Chu, X Wang, W Xu - Biosensors and Bioelectronics, 2023 - Elsevier
Riboswitches are ideal, diverse regulatory elements with simple mechanisms. Therefore,
they are widely employed in synthetic biology to construct highly efficient biosensors for …

Multidimensional Applications and Challenges of Riboswitches in Biosensing and Biotherapy

Y Wu, L Zhu, Y Zhang, W Xu - Small, 2024 - Wiley Online Library
Riboswitches have received significant attention over the last two decades for their multiple
functionalities and great potential for applications in various fields. This article highlights and …

Investigating the Effect of RNA Scaffolds on the Multicolor Fluorogenic Aptamer Pepper in Different Bacterial Species

MM Mumbleau, F Chevance, K Hughes… - ACS Synthetic …, 2024 - ACS Publications
RNA synthetic biology tools have primarily been applied in E. coli; however, many other
bacteria are of industrial and clinical significance. Thus, the multicolor fluorogenic aptamer …

Knotty is nice: metabolite binding and RNA-mediated gene regulation by the preQ1 riboswitch family

D Kiliushik, C Goenner, M Law, GM Schroeder… - Journal of Biological …, 2024 - jbc.org
Riboswitches sense specific cellular metabolites, leading to messenger RNA conformational
changes that regulate downstream genes. Here, we review the three known prequeosine 1 …