The fifth edition of the WHO classification of mature B‐cell neoplasms: open questions for research

SE Coupland, MQ Du, JA Ferry… - The Journal of …, 2024 - Wiley Online Library
The fifth edition of the World Health Organization Classification of Haematolymphoid
Tumours (WHO‐HAEM5) is the product of an evidence‐based evolution of the revised fourth …

Hairy cell leukemia: where are we in 2023?

A Mendez-Hernandez, K Moturi, V Hanson… - Current Oncology …, 2023 - Springer
Abstract Purpose of Review This article summarizes the current state of knowledge of hairy
cell leukemia (HCL) regarding presentation, diagnosis, therapy, and monitoring, including …

Immunophenotypic analysis of hairy cell leukemia (HCL) and hairy cell leukemia-like (HCL-like) disorders

E Maitre, E Cornet, V Salaün, P Kerneves, S Chèze… - Cancers, 2022 - mdpi.com
Simple Summary Hairy cell leukemia (HCL) is a rare B cell neoplasm that accounts for 2% of
B-cell lymphomas. The diagnosis was based on the presence of abnormal lymphoid cells …

The genomic landscape and clonal evolutionary trajectory of classical hairy cell leukemia

LY Moreno Rueda, D Bryant, WJ Tapper… - Leukemia, 2023 - nature.com
In understanding clonal evolution in cancer, whole genome sequencing (WGS) provides
unparalleled data that can be leveraged to derive tumor phylogenies. Specifically, estimates …

Hairy cell leukemia patients have a Normal life expectancy—a 35-year single-center experience and comparison with the general population

JP Bohn, S Neururer, M Pirklbauer, A Pircher, D Wolf - Cancers, 2022 - mdpi.com
Simple Summary Classic hairy cell leukemia (HCL) is a rare, chronic B-cell malignancy with
long-term remissions after standard treatment with purine analogues introduced in the …

[HTML][HTML] A 3-decade multicenter European experience with cladribine as upfront treatment in 384 patients with hairy cell leukemia

A Broccoli, L Argnani, M Cross, A Janus, E Maitre… - Blood Advances, 2022 - Elsevier
Methods Disease-specific patient records have been reviewed at each center, and all
patients requiring treatment who received frontline cladribine have been extrapolated …

Functional genomics and systems biology of Cordyceps species for biotechnological applications

N Raethong, R Thananusak, P Cheawchanlertfa… - Current Opinion in …, 2023 - Elsevier
Highlights●The genus Cordyceps is well known for producing numerous bioactive
compounds with emerging medicinal potentials.●Using integrated omics and systems …

Hairy cell leukemia: a specific 17-gene expression signature points to new targets for therapy

E Maitre, E Cornet, A Debliquis, B Drenou… - Journal of Cancer …, 2022 - Springer
Background Hairy cell leukemia (HCL) is a rare chronic B cell malignancy, characterized by
infiltration of bone marrow, blood and spleen by typical “hairy cells” that bear the …

Purine nucleoside analogs plus rituximab are an effective treatment choice for hairy cell leukemia-variant

Y Wang, T Wang, Y Yu, Q Wang, Y Yan, R Li, Q Sun… - Annals of …, 2022 - Springer
Both characteristics and optimal treatment strategy for hairy cell leukemia-variant (HCL-v)
remain elusive due to its rarity. We retrospectively analyzed the clinical features of HCL-v …

Broadening the horizon: potential applications of CAR-T cells beyond current indications

H Karsten, L Matrisch, S Cichutek, W Fiedler… - Frontiers in …, 2023 - frontiersin.org
Engineering immune cells to treat hematological malignancies has been a major focus of
research since the first resounding successes of CAR-T-cell therapies in B-ALL. Several …