The advent of modern antibiotics contributed enormously to the dramatic extension of
human lifespan since their discovery by virtue of their lethal and selective action against …

Regulation of mRNA translation offers the opportunity to diversify the expression and
abundance of proteins made from individual gene products in cells, tissues and organisms …

Loss of proteostasis is a fundamental process driving aging. Proteostasis is affected by the
accuracy of translation, yet the physiological consequence of having fewer protein synthesis …

Tuberculosis (TB) is a formidable infectious disease that remains a major cause of death
worldwide today. Escalating application of genomic techniques has expedited the …

Background Rapid molecular diagnostics for detecting multidrug-resistant and extensively
drug-resistant tuberculosis (M/XDR-TB) primarily identify mutations in Mycobacterium …

One of the antibiotics used to treat infections is streptomycin sulfate that inhibits both Gram-
negative and-positive bacteria. Nanoparticles are suitable carriers for the direct delivery and …

INTRODUCTION Ribosomes are universally conserved assemblies composed of ribosomal
RNA (rRNA) and proteins, where rRNA plays key structural and functional roles. Despite …

Standard cell culture guidelines often use media supplemented with antibiotics to prevent
cell contamination. However, relatively little is known about the effect of antibiotic use in cell …

Helicobacter pylori, a human pathogen with a high global prevalence, is the causative
pathogen for multiple gastrointestinal diseases, especially chronic gastritis, peptic ulcers …

The emergence of multidrug resistant bacterium threatens to unravel global healthcare
systems, built up over centuries of medical research and development. Current antibiotics …