Brain cancer, especially the most common type of glioblastoma, is highly invasive and
known as one of the most devastating and deadly neoplasms. Despite surgical and medical …

A major obstacle facing brain diseases such as Alzheimer's disease, multiple sclerosis,
brain tumors, and strokes is the blood–brain barrier (BBB). The BBB prevents the passage of …

Nanocarriers have become an effective strategy to overcome epithelial absorption barriers.
During the absorption process, the endocytosis mechanisms, cell internalization pathways …

In the drug delivery field, there is beyond doubt that the shape of micro-and nanoparticles
(M&NPs) critically affects their biological fate. Herein, following an introduction describing …

Recent studies have revealed the effects of shape on in vivo nanoparticle circulation,
distribution, extravasation, and cellular uptake. Morphology is therefore becoming a key …

Brain injuries affect a large patient population with major physical and emotional suffering
for patients and their relatives; at a significant cost to the society. Effective diagnostic and …

Natural polysaccharides and proteins have been widely explored for the preparation of
hydrogel matrices due to their promising biocompatibility and biodegradability. However, it is …

Drug delivery to the brain is challenging due to a highly regulated blood-brain barrier (BBB)
and a complex brain microenvironment. Nanoparticles, due to their tailorability, provide …

Mucosal tissues constitute the largest interface between the body and the surrounding
environment and they regulate the access of molecules, supramolecular structures …

Non-spherical metal nanomaterials such as noble metal or transition metal dichalcogenides
and MXenes have been employed in different biomedical facets. Because the biological …