HIV/AIDS epidemiology, pathogenesis, prevention, and treatment

V Simon, DD Ho, QA Karim - The Lancet, 2006 - thelancet.com
The HIV-1 pandemic is a complex mix of diverse epidemics within and between countries
and regions of the world, and is undoubtedly the defining public-health crisis of our time …

Patient retention in antiretroviral therapy programs in sub-Saharan Africa: a systematic review

S Rosen, MP Fox, CJ Gill - PLoS medicine, 2007 - journals.plos.org
Background Long-term retention of patients in Africa's rapidly expanding antiretroviral
therapy (ART) programs for HIV/AIDS is essential for these programs' success but has …

Guidelines for improving entry into and retention in care and antiretroviral adherence for persons with HIV: evidence-based recommendations from an International …

MA Thompson, MJ Mugavero, KR Amico… - Annals of internal …, 2012 - acpjournals.org
Description: After HIV diagnosis, timely entry into HIV medical care and retention in that care
are essential to the provision of effective antiretroviral therapy (ART). Adherence to ART is …

Non-nucleoside reverse transcriptase inhibitors (NNRTIs), their discovery, development, and use in the treatment of HIV-1 infection: a review of the last 20 years (1989 …

MP de Béthune - Antiviral research, 2010 - Elsevier
It is almost 20 years since NNRTIs were identified as a new class of antiretroviral drugs for
the treatment of HIV-1 infection. Although they belong to different and diverse chemical …

The WHO public-health approach to antiretroviral treatment against HIV in resource-limited settings

CF Gilks, S Crowley, R Ekpini, S Gove, J Perriens… - The lancet, 2006 - thelancet.com
WHO has proposed a public-health approach to antiretroviral therapy (ART) to enable
scaling-up access to treatment for HIV-positive people in developing countries, recognising …

Early mortality among adults accessing antiretroviral treatment programmes in sub-Saharan Africa

SD Lawn, AD Harries, X Anglaret, L Myer, R Wood - Aids, 2008 - journals.lww.com
Two-thirds of the world's HIV-infected people live in sub-Saharan Africa, and more than 1.5
million of them die annually. As access to antiretroviral treatment has expanded within the …

Mortality of patients lost to follow-up in antiretroviral treatment programmes in resource-limited settings: systematic review and meta-analysis

MWG Brinkhof, M Pujades-Rodriguez, M Egger - PloS one, 2009 - journals.plos.org
Background The retention of patients in antiretroviral therapy (ART) programmes is an
important issue in resource-limited settings. Loss to follow up can be substantial, but it is …

Effect of earlier initiation of antiretroviral treatment and increased treatment coverage on HIV-related mortality in China: a national observational cohort study

F Zhang, Z Dou, Y Ma, Y Zhang, Y Zhao… - The Lancet infectious …, 2011 - thelancet.com
Background Overall HIV mortality rates in China have not been reported. In this analysis we
assess overall mortality in treatment-eligible adults with HIV and attempt to identify risk …

The spread, treatment, and prevention of HIV-1: evolution of a global pandemic

MS Cohen, N Hellmann, JA Levy… - The Journal of …, 2008 - Am Soc Clin Investig
The most up-to-date estimates demonstrate very heterogeneous spread of HIV-1, and more
than 30 million people are now living with HIV-1 infection, most of them in sub-Saharan …

Rapid scale-up of antiretroviral therapy at primary care sites in Zambia: feasibility and early outcomes

JSA Stringer, I Zulu, J Levy, EM Stringer, A Mwango… - Jama, 2006 - jamanetwork.com
ContextThe Zambian Ministry of Health has scaled-up human immunodeficiency
virus/acquired immunodeficiency syndrome (HIV/AIDS) care and treatment services at …