Gallbladder cancer (GBC) is the most common cancer of the biliary tract, characterized by a
very poor prognosis when diagnosed at advanced stages owing to its aggressive behaviour …

Simple Summary Gallbladder cancer is the sixth cause of death related to digestive tract
tumors, with high mortality due to delayed diagnosis at advanced stages of the disease …

Background and Aims Gallbladder cancer (GBC) is a highly aggressive malignancy of the
biliary tract. Most cases of GBC are diagnosed in low‐income and middle‐income countries …

Conclusions Our results indicate that GBC carcinogenesis comprises three main methylation
stages: early (gallstone disease and low‐grade dysplasia), intermediate (high‐grade …

Background Heterozygous ABCB4 variants are not routinely tested in adults with cholestasis
because of their supposed rarity and high costs. Methods Nineteen adult patients presenting …

Compelling evidence derived from clinical and experimental research has demonstrated the
crucial contribution of chronic inflammation in the development of neoplasms, including …

On a global scale, gallbladder cancer is a relatively rare cancer with a striking variability in
incidence across countries and world regions. We examined recent geographic variations …

Introduction The incidence of biliary system diseases has been continuously increasing in
the past decade. Biliary system diseases bring a heavy burden to humanity and society …

Gallbladder cancer (GBC) is an aggressive disease with limited treatment options but high
prevention potential. GBC tumours take 10–20 years to develop, a timeframe that holds …

The function of ABC transporters in the body is manifold; such as maintenance of
homeostasis, effect on multi-drug resistance and their role in tumor initiation & progression …