Physiological roles of hydrogen sulfide in mammalian cells, tissues, and organs

G Cirino, C Szabo… - Physiological …, 2023 - journals.physiology.org
Over the last two decades, hydrogen sulfide (H2S) has emerged as an endogenous
regulator of a broad range of physiological functions. H2S belongs to the class of molecules …

Production of hydrogen sulfide by the intestinal microbiota and epithelial cells and consequences for the colonic and rectal mucosa

F Blachier, M Andriamihaja… - American Journal …, 2021 - journals.physiology.org
Among bacterial metabolites, hydrogen sulfide (H2S) has received increasing attention. The
epithelial cells of the large intestine are exposed to two sources of H2S. The main one is the …

Hydrogen sulfide signaling in plant adaptations to adverse conditions: molecular mechanisms

A Aroca, J Zhang, Y Xie, LC Romero… - Journal of Experimental …, 2021 - academic.oup.com
Hydrogen sulfide (H2S) is a signaling molecule that regulates critical processes and allows
plants to adapt to adverse conditions. The molecular mechanism underlying H2S action …

Hydrogen sulfide produced by gut bacteria may induce Parkinson's disease

KE Murros - Cells, 2022 - mdpi.com
Several bacterial species can generate hydrogen sulfide (H2S). Study evidence favors the
view that the microbiome of the colon harbors increased amounts of H2S producing bacteria …

[HTML][HTML] Interactions of reactive sulfur species with metalloproteins

A Domán, É Dóka, D Garai, V Bogdándi, G Balla… - Redox Biology, 2023 - Elsevier
Reactive sulfur species (RSS) entail a diverse family of sulfur derivatives that have emerged
as important effector molecules in H 2 S-mediated biological events. RSS (including H 2 S) …

Hydrogen sulfide and persulfides oxidation by biologically relevant oxidizing species

D Benchoam, E Cuevasanta, MN Möller, B Alvarez - Antioxidants, 2019 - mdpi.com
Hydrogen sulfide (H2S/HS–) can be formed in mammalian tissues and exert physiological
effects. It can react with metal centers and oxidized thiol products such as disulfides (RSSR) …

Hydrosulfide complexes of the transition elements: diverse roles in bioinorganic, cluster, coordination, and organometallic chemistry

MD Pluth, ZJ Tonzetich - Chemical Society Reviews, 2020 - pubs.rsc.org
Sulfur-based ligands are versatile donors that play important roles in a wide array of
subdisciplines of inorganic chemistry including organometallic chemistry, bioinorganic …

The reactive species interactome in red blood cells: oxidants, antioxidants, and molecular targets

MM Cortese-Krott - Antioxidants, 2023 - mdpi.com
Beyond their established role as oxygen carriers, red blood cells have recently been found
to contribute to systemic NO and sulfide metabolism and act as potent circulating antioxidant …

Hydrogen Sulfide Ligation in Hemoglobin I of Lucina pectinata─A QM/MM and Local Mode Study

M Freindorf, J Antonio, E Kraka - The Journal of Physical …, 2023 - ACS Publications
In this study, we investigated the interaction between the H2S ligand and the heme pocket of
hemoglobin I (HbI) of Lucina pectinata for the wild-type protein; three known mutations …

[HTML][HTML] Overview on hydrogen sulfide-mediated suppression of vascular calcification and hemoglobin/heme-mediated vascular damage in atherosclerosis

T Gáll, P Nagy, D Garai, L Potor, GJ Balla, G Balla… - Redox Biology, 2022 - Elsevier
Vulnerable atherosclerotic plaques with hemorrhage considerably contribute to
cardiovascular morbidity and mortality. Calcification is the main characteristic of advanced …