Therapeutic antibodies in medicine

P Sharma, RV Joshi, R Pritchard, K Xu, MA Eicher - Molecules, 2023 - mdpi.com
Antibody engineering has developed into a wide-reaching field, impacting a multitude of
industries, most notably healthcare and diagnostics. The seminal work on developing the …

The aggressive diabetic kidney disease in youth-onset type 2 diabetes: pathogenetic mechanisms and potential therapies

M Amatruda, G Gembillo, AE Giuffrida, D Santoro… - Medicina, 2021 - mdpi.com
Youth-onset Type 2 Diabetes Mellitus (T2DM) represents a major burden worldwide. In the
last decades, the prevalence of T2DM became higher than that of Type 1 Diabetes Mellitus …

Spectrum of podocytopathies in new-onset nephrotic syndrome following COVID-19 disease: a report of 2 cases

RK Gupta, R Bhargava, AA Shaukat, E Albert, J Leggat - BMC nephrology, 2020 - Springer
Abstract Background Coronavirus disease-2019 (COVID-19) is an ongoing pandemic which
has affected over 12 million people across the globe. Manifestations in different organs …

Efficacy and safety of rituximab in adult frequent-relapsing or steroid-dependent minimal change disease or focal segmental glomerulosclerosis: a systematic review …

C Xue, B Yang, J Xu, C Zhou, L Zhang… - Clinical Kidney …, 2021 - academic.oup.com
Background The efficacy and safety of rituximab (RTX) in adult frequent-relapsing (FR) or
steroid-dependent (SD) nephrotic syndrome (NS), including minimal change disease (MCD) …

Nephrotic syndrome

E Rodriguez-Ballestas, J Reid-Adam - Pediatrics in review, 2022 - publications.aap.org
Nephrotic syndrome (NS) encompasses a variety of disease processes leading to heavy
proteinuria and edema. Minimal change disease (MCD) remains the most common primary …

The role of platelet-derived growth factor in focal segmental glomerulosclerosis

T Jia, T Xu, B Smeets, EM Buhl… - Journal of the …, 2023 - journals.lww.com
Background FSGS is the final common pathway to nephron loss in most forms of severe or
progressive glomerular injury. Although podocyte injury initiates FSGS, parietal epithelial …

Clinicopathologic correlations of renal biopsy findings from northeast China: a 10-year retrospective study

S Su, J Yu, Y Wang, Y Wang, J Li, Z Xu - Medicine, 2019 - journals.lww.com
Clinicopathologic correlations of renal biopsy findings from... : Medicine Clinicopathologic
correlations of renal biopsy findings from northeast China: A 10-year retrospective study …

Insight into the role of angiopoietin‑like protein 4 in podocypopathies

V Calabrese, F Zirino, FG Vienna… - World Academy of …, 2024 - spandidos-publications.com
Angiopoietin‑like proteins are a group of seven proteins whose structure is different from that
of angiopoietins in linkage to Tie2 or Tie1 receptors. Angiopoietin‑like protein 4 (ANGPTL4) …

Serum IgE levels are a risk factor with prognosis of pediatric minimal change disease

T Han, M Xue, Y Guan, T Ju, K Shi, M Fu, L Jia… - Frontiers in …, 2023 - frontiersin.org
Background Minimal change disease (MCD) is one of the most common primary glomerular
disorders with high serum IgE levels. This study was aimed to investigate the clinical …

[PDF][PDF] Diverse immunopathological manifestations and immunogenomic predispositions in COVID-19: summarizing the evidence

S Deb, R Mondal, D Lahiri, U Ganguly… - International Journal of …, 2022 - academia.edu
The COVID-19 pandemic has caused immense damage to most nations of the world, both in
terms of loss of human lives, as well as, socio-economic attributes. The …