[HTML][HTML] Augmented glycerosomes as a promising approach against fungal ear infection: Optimization and microbiological, ex vivo and in vivo assessments

S Ahmed, H Attia, O Saher, AM Fahmy - International Journal of …, 2024 - Elsevier
In the current study, voriconazole (VCZ) augmented glycerosomes were optimized for topical
otomycosis management according to a 2 3 factorial design, employing a thin film hydration …

Nano-vesicular systems for melanocytes targeting and melasma treatment: In-vitro characterization, ex-vivo skin retention, and preliminary clinical appraisal

S Hatem, AO Kamel, SA Elkheshen, M Nasr… - International Journal of …, 2024 - Elsevier
Melasma represents an acquired melanogenesis disorder resulting in skin's
hyperpigmentation effect. Although several approaches are adopted for melasma treatment …

Future Prospects and Regulatory Pathways for Invasome Technologies in Transdermal Drug Delivery

D Kumar, D Sil, BD Kurmi, M Kumar - ASSAY and Drug …, 2025 - liebertpub.com
Skin is one of the largest organs in the human body. It acts as an outer protective cover and
comprises the epidermis, dermis, and hypodermis. Liposomes are formed by phospholipids …

Optimizing nutraceutical-loaded trehalosomes in-situ gel for diabetic cataract management: Comprehensive in vitro and in vivo evaluations

A Hussein, M El-Kayal, RN Shamma, HH Awad… - Journal of Drug Delivery …, 2024 - Elsevier
This study aimed to develop Baicalin-loaded trehalosomes in situ gel (BA-THs-ISG) for the
treatment of cataract, a degenerative eye condition that requires innovative approaches to …

Development and in vitro tuning of empagliflozin-containing dissolvable microneedle patch for enhanced transdermal delivery

A Javed, RM Sarfraz, A Mahmood, Z Ahmad… - Naunyn-Schmiedeberg's …, 2024 - Springer
This painless method allows drugs to penetrate the outer skin layer, offering several
advantages over alternative administration routes, including ease of use and the ability to …