CD8+ tissue resident memory T cells (TRM cells) are essential for immune defence against
pathogens and malignancies, and the molecular processes that lead to TRM cell formation …

Throughout life, T cells coordinate multiple aspects of adaptive immunity, including
responses to pathogens, allergens, and tumors. In mouse models, the role of T cells is …

These guidelines are a consensus work of a considerable number of members of the
immunology and flow cytometry community. They provide the theory and key practical …

Tissue-resident immune cells span both myeloid and lymphoid cell lineages, have been
found in multiple human tissues, and play integral roles at all stages of the immune …

From a technical point of view a flow cytometer is a light detection device capable of
detecting photons of different wavelengths over a high dynamic range. In order to achieve a …

T cells differentiate into functionally distinct states upon antigen encounter. These states are
delineated by different cell surface markers for murine and human T cells, which hamper …

The expression of CD45RA is generally associated with naive T cells. However, a subset of
effector memory T cells re-expresses CD45RA (termed TEMRA) after antigenic stimulation …

Tissue-resident memory T (Trm) cells permanently localize to portals of pathogen entry,
where they provide immediate protection against reinfection. To enforce tissue retention …

Immune responses in tissues are constrained by the physiological properties of the tissue
involved. Tissue-resident memory T cells (TRM cells) are a recently discovered lineage of T …

The liver provides a tolerogenic immune niche exploited by several highly prevalent
pathogens as well as by primary and metastatic tumors. We have sampled healthy and …