Networking of the human cerebellum: From anatomo-functional development to neurosurgical implications

A De Benedictis, MC Rossi-Espagnet… - Frontiers in …, 2022 - frontiersin.org
In the past, the cerebellum was considered to be substantially involved in sensory-motor
coordination. However, a growing number of neuroanatomical, neuroimaging, clinical and …

Comparative connectivity correlates of dystonic and essential tremor deep brain stimulation

T Tsuboi, JK Wong, RS Eisinger, L Okromelidze… - Brain, 2021 - academic.oup.com
The pathophysiology of dystonic tremor and essential tremor remains partially understood.
In patients with medication-refractory dystonic tremor or essential tremor, deep brain …

The dentato-rubro-thalamic tract as the potential common deep brain stimulation target for tremor of various origin: an observational case series

VA Coenen, B Sajonz, T Prokop, M Reisert, T Piroth… - Acta …, 2020 - Springer
Introduction Deep brain stimulation alleviates tremor of various origins. The dentato-rubro-
thalamic tract (DRT) has been suspected as a common tremor-reducing structure. Statistical …

Personalizing deep brain stimulation using advanced imaging sequences

C Neudorfer, D Kroneberg, B Al‐Fatly… - Annals of …, 2022 - Wiley Online Library
Objective With a growing appreciation for interindividual anatomical variability and patient‐
specific brain connectivity, advanced imaging sequences offer the opportunity to directly …

[HTML][HTML] Brain connectometry changes in space travelers after long-duration spaceflight

A Doroshin, S Jillings, B Jeurissen… - Frontiers in neural …, 2022 - frontiersin.org
Humans undergo extreme physiological changes when subjected to long periods of
weightlessness, and as we continue to become a space-faring species, it is imperative that …

Role of cerebellar GABAergic dysfunctions in the origins of essential tremor

X Zhang, S Santaniello - Proceedings of the National …, 2019 - National Acad Sciences
Essential tremor (ET) is among the most prevalent movement disorders, but its origins are
elusive. The inferior olivary nucleus (ION) has been hypothesized as the prime generator of …

Comparative evaluation of tractography-based direct targeting and atlas-based indirect targeting of the ventral intermediate (Vim) nucleus in MRgFUS thalamotomy

F Bruno, A Catalucci, M Varrassi, F Arrigoni… - Scientific Reports, 2021 - nature.com
To analyze and compare direct and indirect targeting of the Vim for MRgFUS thalamotomy.
We retrospectively evaluated 21 patients who underwent unilateral MRgFUS Vim ablation …

[HTML][HTML] Connectivity correlates to predict essential tremor deep brain stimulation outcome: evidence for a common treatment pathway

EH Middlebrooks, L Okromelidze, JK Wong… - NeuroImage: Clinical, 2021 - Elsevier
Background and purpose Deep brain stimulation (DBS) is the most common surgical
treatment for essential tremor (ET), yet there is variation in outcome and stimulation targets …

[HTML][HTML] Olivocerebellar control of movement symmetry

V Romano, P Zhai, A van der Horst, R Mazza, T Jacobs… - Current Biology, 2022 - cell.com
Coordination of bilateral movements is essential for a large variety of animal behaviors. The
olivocerebellar system is critical for the control of movement, but its role in bilateral …

Fiber-specific micro-and macroscopic white matter alterations in progressive supranuclear palsy and corticobasal syndrome

W Uchida, K Kamagata, C Andica… - npj Parkinson's …, 2023 - nature.com
Progressive supranuclear palsy (PSP) and corticobasal syndrome (CBS) are characterized
by progressive white matter (WM) alterations associated with the prion-like spreading of four …