Biomedical applications of calixarenes: state of the art and perspectives

YC Pan, XY Hu, DS Guo - Angewandte Chemie International …, 2021 - Wiley Online Library
Calixarenes (CAs), representing the third generation of supramolecular hosts and one of the
most widely studied macrocyclic scaffolds, offer (almost) unlimited structure and application …

[HTML][HTML] On the design principles of peptide–drug conjugates for targeted drug delivery to the malignant tumor site

EI Vrettos, G Mező, AG Tzakos - Beilstein journal of organic …, 2018 - beilstein-journals.org
Cancer is the second leading cause of death affecting nearly one in two people, and the
appearance of new cases is projected to rise by> 70% by 2030. To effectively combat the …

Assembling features of calixarene-based amphiphiles and supra-amphiphiles

HW Tian, YC Liu, DS Guo - Materials Chemistry Frontiers, 2020 - pubs.rsc.org
Macrocyclic amphiphiles as an emerging family of artificial amphiphiles have gained
considerable attention in recent years on account of their fascinating recognition and …

Supramolecular Luminescent Nano‐assemblies Based on Macrocycles and Amphiphiles for Cell Imaging

N Qian, XF Hou, Y Tang, S Zhang, XM Chen… - …, 2023 - Wiley Online Library
Supramolecular luminescent nano‐assemblies for cell imaging have recently attracted
increasing interest, not only because of their outstanding photophysical properties, but also …

Synthesis and anticancer activity of new p-tertbutylcalix [4] arenes integrated with trifluoromethyl aniline groups against several cell lines

M Oguz - Tetrahedron, 2022 - Elsevier
A new series of p-tertbutylcalix [4] arenes integrated with isomer trifluoromethyl anilines has
been designed as potential anticancer agents. The integration of trifluoromethyl anilines to p …

Inclusion of quercetin in gold nanoparticles decorated with supramolecular hosts amplifies its tumor targeting properties

M Yilmaz, AA Karanastasis… - ACS Applied Bio …, 2019 - ACS Publications
Despite the anticancer potential of natural products (NPs), their limited bioavailability
necessitates laborious derivatization or covalent conjugation to delivery vehicles. To …

Synthesis and evaluation of the antitumor activity of Calix [4] arene L-proline derivatives

M Oguz, A Gul, S Karakurt, M Yilmaz - Bioorganic chemistry, 2020 - Elsevier
The unique conformational properties, functionality, low toxicity, and low cost make
calixarene-based compounds a valuable candidate against cancer. The aim of the present …

Encapsulation of temozolomide in a calixarene nanocapsule improves its stability and enhances its therapeutic efficacy against glioblastoma

A Renziehausen, AD Tsiailanis, R Perryman… - Molecular cancer …, 2019 - AACR
The alkylating agent temozolomide (TMZ) is the first-line chemotherapeutic for glioblastoma
(GBM), a common and aggressive primary brain tumor in adults. However, its poor stability …

Calixarene: a versatile material for drug design and applications

MA Hussain, MU Ashraf, G Muhammad… - Current …, 2017 - ingentaconnect.com
The therapy of various diseases by the drugs entrapped in calixarene derivatives is gaining
attraction of researchers nowadays. Calixarenes are macrocyclic nano-baskets which …

Calixarenes: recent progress in supramolecular chemistry for application in cancer therapy

A Isik, M Oguz, A Kocak, M Yilmaz - Journal of Inclusion Phenomena and …, 2022 - Springer
Cancer is one of the leading causes of death worldwide, and the limited success of currently
used anticancer drugs is a driving force for the search for new compounds with anticancer …