Atomic scale determination of enzyme flexibility and active site stability through static modes: case of dihydrofolate reductase

M Brut, A Esteve, G Landa, G Renvez… - The Journal of …, 2011 - ACS Publications
A Static Mode approach is used to screen the biomechanical properties of DHFR. In this
approach, a specific external stimulus may be designed at the atomic scale granularity to …

Toward in silico biomolecular manipulation through static modes: atomic scale characterization of HIV-1 protease flexibility

M Brut, A Estève, G Landa… - The Journal of Physical …, 2014 - ACS Publications
Probing biomolecular flexibility with atomic-scale resolution is a challenging task in current
computational biology for fundamental understanding and prediction of biomolecular …

[PDF][PDF] Mimicking DNA stretching with the Static Mode method: Shear stress versus transverse pulling stress

M Brut, A Estève, G Landa… - The European Physical …, 2012 - Springer
DNA sequencing using nanopores is closer than ever to become a reality, but further
research and development still need to be done, especially to unravel the atomic-scale …