Low-energy electron damage to condensed-phase DNA and its constituents

Y Gao, Y Zheng, L Sanche - International Journal of Molecular Sciences, 2021 - mdpi.com
The complex physical and chemical reactions between the large number of low-energy (0–
30 eV) electrons (LEEs) released by high energy radiation interacting with genetic material …

Reaction of electrons with DNA: radiation damage to radiosensitization

A Kumar, D Becker, A Adhikary, MD Sevilla - International Journal of …, 2019 - mdpi.com
This review article provides a concise overview of electron involvement in DNA radiation
damage. The review begins with the various states of radiation-produced electrons …

The Physico‐Chemical Basis of DNA Radiosensitization: Implications for Cancer Radiation Therapy

R Schürmann, S Vogel, K Ebel… - Chemistry–A European …, 2018 - Wiley Online Library
High‐energy radiation is used in combination with radiosensitizing therapeutics to treat
cancer. The most common radiosensitizers are halogenated nucleosides and cisplatin …

Secondary electron attachment-induced radiation damage to genetic materials

J Narayanan SJ, D Tripathi, P Verma, A Adhikary… - ACS …, 2023 - ACS Publications
Reactions of radiation-produced secondary electrons (SEs) with biomacromolecules (eg,
DNA) are considered one of the primary causes of radiation-induced cell death. In this …

A NaI/H2O2-Mediated Sulfenylation and Selenylation of Unprotected Uracil and Its Derivatives

XD Li, YT Gao, YJ Sun, XY Jin, D Wang, L Liu… - Organic …, 2019 - ACS Publications
An efficient iodide-catalyzed/hydrogen peroxide mediated sulfenylation and selenylation of
unprotected uracil and its derivatives with simple thiols and diselenides was established …

Intramolecular interactions in derivatives of uracil tautomers

PA Wieczorkiewicz, TM Krygowski, H Szatylowicz - Molecules, 2022 - mdpi.com
The influence of solvents on intramolecular interactions in 5-or 6-substituted nitro and amino
derivatives of six tautomeric forms of uracil was investigated. For this purpose, the density …

Nitro rotation tuned dissociative electron attachment upon targeted radiosensitizer 4-substituted Z bases

X Cui, Y Zhao, C Zhang, Q Meng - Physical Chemistry Chemical …, 2022 - pubs.rsc.org
In this work, a set of new potential radiation sensitizers (4-substituted Z-bases: 4XZ, X= F, Cl,
Br, and I) are designed based on the artificial 6-amino-5-nitro-3-(1′-β-D-2 …

Electron-induced dissociation of the potential radiosensitizer 5-selenocyanato-2′-deoxyuridine

R Meißner, S Makurat, W Kozak… - The Journal of …, 2019 - ACS Publications
5-Selenocyanato-2′-deoxyuridine (SeCNdU) is a recently proposed radiosensitizer based
on 2′-deoxyuridine (dU) with the electron-affinic selenocyanato (− SeCN) side group …

Damage Induced to DNA and Its Constituents by 0–3 eV UV Photoelectrons

C Liu, Y Zheng, L Sanche - Photochemistry and Photobiology, 2022 - Wiley Online Library
The complex physical and chemical interactions between DNA and 0–3 eV electrons
released by UV photoionization can lead to the formation of various lesions such as base …

Quasi-Free Electron-Mediated Radiation Sensitization by C5-Halopyrimidines

J Ma, T Bahry, SA Denisov, A Adhikary… - The Journal of …, 2021 - ACS Publications
Substitution of the thymidine moiety in DNA by C5-substituted halogenated thymidine
analogues causes significant augmentation of radiation damage in living cells. However, the …