Genotype-to-phenotype mapping commonly focuses on two major classes of mutations:
single nucleotide polymorphisms (SNPs) and copy number variation (CNV). Here, we …

DNA tandem repeats (TRs), also designated as satellite DNA, are inter-or intragenic
nucleotide sequences that are repeated two or more times in a head-to-tail manner …

ABSTRACT Nontypeable Haemophilus influenzae (NTHi) is a leading causative agent of
otitis media. Much of the inflammation occurring during NTHi disease is initiated by …

The respiratory tract pathogen Haemophilus influenzae is responsible for a variety of
infections in humans including septicemia, bronchitis, pneumonia, and acute otitis media …

Tracking bacterial evolution during chronic infection provides insights into how host
selection pressures shape bacterial genomes. The human-restricted opportunistic pathogen …

Pathogenic bacteria employ many strategies to overcome the host immune system for
extended survival and propagation in their hosts. Components of the bacterial outer …

The complement system is an important first line of defense against the human pathogen
Haemophilus influenzae. To survive and propagate in vivo, H. influenzae has evolved …

Nontypeable Haemophilus influenzae (NTHI) is an extremely common airway commensal
which can cause opportunistic infections that are usually localized to airway mucosal …

There are 16 capsule-based serotypes of Actinobacillus pleuropneumoniae, all of which are
capable of causing disease in pigs. Here we report the finished and annotated genome …

We are investigating a nontypeable Haemophilus influenzae (NTHI) strain, R2866, isolated
from a child with meningitis. R2866 is unusually resistant to killing by normal human serum …