Pharmacological activity of flavonoid quercetin and its therapeutic potential in testicular injury

X Zhang, Y Tang, G Lu, J Gu - Nutrients, 2023 - mdpi.com
Quercetin is a natural flavonoid widely found in natural fruits and vegetables. Recent studies
have shown that quercetin mediates multiple beneficial effects in a variety of organ damage …

Pharmacological action of quercetin against testicular dysfunction: A mini review

DE Rotimi, TD Olaolu, OS Adeyemi - Journal of Integrative Medicine, 2022 - Elsevier
The testis is an immune-privileged organ susceptible to oxidative stress and inflammation,
two major factors implicated in male infertility. A reduction in the concentration and activities …

Ameliorative effects of quercetin against hepatic toxicity of oral sub-chronic co-exposure to aluminum oxide nanoparticles and lead-acetate in male rats

K Abo-EL-Sooud, YM Abd-Elhakim… - Naunyn-Schmiedeberg's …, 2023 - Springer
The present study was designed to evaluate the probable ameliorative role of quercetin
(QCN) against oxidative hepatotoxicity induced by aluminum oxide nanoparticles …

Probing the potential mechanism of quercetin and kaempferol against heat stress-induced sertoli cell injury: through integrating network pharmacology and …

DL Liu, SJ Liu, SQ Hu, YC Chen, J Guo - International Journal of …, 2022 - mdpi.com
Quercetin and kaempferol are flavonoids widely present in fruits, vegetables, and medicinal
plants. They have attracted much attention due to their antioxidant, anti-inflammatory …

Long-term exposure to the mixture of phthalates induced male reproductive toxicity in rats and the alleviative effects of quercetin

LL Liu, JZ Yue, ZY Lu, RY Deng, CC Li, YN Yu… - Toxicology and Applied …, 2024 - Elsevier
Phthalates (PEs), such as di (2-ethylhexyl) phthalate (DEHP), dibutyl phthalate (DBP) and
butyl benzyl phthalate (BBP) could cause reproductive and developmental toxicities, while …

Potential protective effect of quercetin on the male reproductive system against exposure of Wistar rats to crude oil vapor: Genetic, biochemical, and histopathological …

K Khazaeel, SAZ Daaj, A Sadeghi, MR Tabandeh… - Reproductive …, 2022 - Elsevier
Toxic compounds in crude oil vapor (COV), including polycyclic aromatic hydrocarbons
(PAHs), are associated with adverse effects on reproduction in living organisms. Quercetin …

Reproductive and embryological toxicity of lead acetate in male mice and their offspring and mitigation effects of quercetin

P Dolati, MJ Zamiri, A Akhlaghi, Z Khodabandeh… - Journal of Trace …, 2021 - Elsevier
Exposure to heavy metals not only impacts on fertility in males, it may also affect the
offspring. The aim of the present study was to examine the toxic effects of lead acetate on …

Resveratrol ameliorates bisphenol A-induced testicular toxicity in adult male rats: a stereological and functional study

H Bordbar, SS Yahyavi, A Noorafshan… - Basic and Clinical …, 2023 - Springer
Abstract Background Bisphenol A (BPA) is one of the most widely used synthetic chemicals
worldwide. BPA as an endocrine disruptor affects the reproductive systems through …

Thymoquinone ameliorates bleomycin-induced reproductive toxicity in male Balb/c mice

L Yaghutian Nezhad… - Human & …, 2021 - journals.sagepub.com
Bleomycin (BL) is a powerful chemotherapy drug that has devastating effects on
spermatogenic function and may make cancer survivors at risk of infertility. Protective effects …

[PDF][PDF] In silico analysis of quercetin and its analogues against targeted proteins

A Sekar, R Soundhararajan… - Biointerface Res. Appl …, 2021 - biointerfaceresearch.com
Quercetin is a flavonoid compound present in many plants such as onions, tomatoes,
apples, green tea, flax seeds, etc. It possesses antioxidant and anti-inflammatory effects that …