Chemometrics approaches to green analytical chemistry procedure development

K Kalinowska, M Bystrzanowska… - Current Opinion in Green …, 2021 - Elsevier
Chemometric tools are widely used in analytical chemistry for the reduction of data
dimensionality, grouping of variables, and processing of analytical signals. They have also …

Whiteness and greenness assessment with efficacy evaluation of two UPLC systems applied for the quantification of cinnarizine and dimenhydrinate along with their …

EM Morgan, HM Lotfy, RH Obaydo, YM Fayez… - Sustainable Chemistry …, 2023 - Elsevier
Fixed-dose combination of cinnarizine (CIN) and dimenhydrinate (DMH) is an effective
therapy for patients diagnosed for having central and/or peripheral vestibular disorder …

ChlorTox scale assessment, greenness, and whiteness evaluation of selective spectrophotometric analysis of dimenhydrinate and cinnarizine

EM Morgan, YM Fayez, SA Boltia, RH Obaydo… - … Acta Part A: Molecular …, 2024 - Elsevier
Nausea and vomiting are considered common series side effects induced by chemotherapy
treatment in cancer patients. This annoying side effect can impair the patient's compliance to …

1-Benzhydryl-piperazine: Isolation, structure determination, and in silico studies for a novel potential narcotic agent detected in sports supplements

Z Arslan, E Okuroğlu, H Şenol, Z Türkmen - Journal of Food Composition …, 2024 - Elsevier
Adulteration of sports supplements poses significant health risks, necessitating stringent
regulatory oversight. This study investigates deceptive practices by manufacturers, including …

Green analytical chemistry metrics and life-cycle assessment approach to analytical method development

MM Abdelrahman - Green chemical analysis and sample preparations …, 2022 - Springer
The environmental consequences of chemical and analytical research, particularly the use
and production of toxic reagents and solvents, have sparked widespread concern …

[HTML][HTML] Novel mucoadhesive chitosomes as a platform for enhanced oral bioavailability of cinnarizine

HA Oransa, MF Boughdady… - International Journal of …, 2022 - ncbi.nlm.nih.gov
Purpose Cinnarizine (CIN) is a class II BSC drug, suffering from erratic bioavailability due to
its pH-dependent solubility. It has preferential absorption in the stomach. In this study, new …

Spectrophotometric Resolution Methods for Determination of Dimenhydrinate and Cinnarizine in Presence of their Toxic Impurities: Greenness, Environmental …

EM Morgan, YM Fayez, SA Boltia… - Bulletin of Faculty of …, 2023 - bfopcu.eg.net
Spectrophotometric analysis of the core drug while the coexistence of their toxic impurities is
a vital analytical process. To date, there was no reported spectrophotometric method that …

A validated, stability-indicating, eco-friendly HPTLC method for the determination of cinnarizine

MH Alqarni, F Shakeel, AI Foudah, TM Aljarba… - Separations, 2023 - mdpi.com
The eco-friendly high-performance thin-layer chromatographic (HPTLC) approaches for
measuring cinnarizine (CIN) are scant in reported databases. As a result, the current work …

Spectrophotometric determination of domperidone maleate, carvedilol, dimetindene maleate and cinnarizine in pharmaceuticals by ion association complex formation …

M Abdullah, E Salih - College Of Basic Education Research …, 2022 - berj.mosuljournals.com
A direct simple, rapid and sensitive spectrophotometric method has been developed for the
determination of domperidone maleate (DOM), carvedilol (CAR), dimetindene maleate …

Green Electrochemical Sensing: Novel Ion-Selective Electrode Method for Precise Determination of Dimenhydrinate and its Metabolite along with Cinnarizine in …

SA Boltia, EM Morgan, RH Obaydo… - Journal of The …, 2024 - iopscience.iop.org
Green and sustainable scientific research is crucial for health and environmental
improvement. Electrochemical analysis simplifies complex processes, saving time and cost …