China has the largest population of patients with dementia in the world, imposing a heavy
burden on the public and health care systems. More than 100 epidemiological studies on …

Dementia is a severe neurodegenerative disorder and it can be categorized into several
subtypes by different pathogenic causes. We sought to comprehensively analyzed the …

Polysomnography (PSG) studies of sleep changes in Alzheimer's disease (AD) have
reported but not fully established the relationship between sleep disturbances and AD. To …

The concept of cognitive reserve provides an explanation for differences between
individuals in susceptibility to age-related brain changes or pathology related to Alzheimer's …

With the aging of the population, the burden of Alzheimer's disease (AD) is rapidly
expanding. More than 5 million people in the US alone are affected with AD and this number …

Background Cognitive impairment, including dementia, is a major health concern with the
increasing aging population. Preventive measures to delay cognitive decline are of utmost …

Alzheimer disease (AD) is biologically defined by the presence of β-amyloid-containing
plaques and tau-containing neurofibrillary tangles. AD is a genetic and sporadic …

The Memory and Aging Project is a longitudinal, epidemiologic clinical-pathologic cohort
study of common chronic conditions of aging with an emphasis on decline in cognitive and …

Objectives To evaluate the effectiveness of the Chinese version of the Montreal Cognitive
Assessment Basic (Mo CA‐BC) as a screening tool for detecting mild cognitive impairment …

The idea of reserve against brain damage stems from the repeated observation that there
does not appear to be a direct relationship between the degree of brain pathology or brain …