Evaluating clinical outcomes and physiological perspectives in studies investigating respiratory support for babies born at term with or at risk of transient tachypnea: a …

EV McGillick, AB Te Pas, T van den Akker… - Frontiers in …, 2022 - frontiersin.org
Respiratory distress in the first few hours of life is a growing disease burden in otherwise
healthy babies born at term (> 37 weeks gestation). Babies born by cesarean section without …

[HTML][HTML] Continuous positive airway pressure for term and≥ 34+ 0 weeks' gestation newborns at birth: A systematic review

BA Shah, JG Fabres, TA Leone, GM Schmölzer… - Resuscitation …, 2022 - Elsevier
Background Respiratory distress is common during transition after birth, but the effect of
continuous positive airway pressure applied in the delivery room has not been …

Slowing lung deflation by increasing the expiratory resistance enhances FRC in preterm rabbits

KLAM Kuypers, J Dekker, KJ Crossley, MJ Wallace… - Pediatric …, 2024 - nature.com
Background As very preterm infants have surfactant-deficient and highly incompliant lungs,
slowing lung deflation during expiration might help preserve functional residual capacity …

Increased airway liquid volumes at birth impair cardiorespiratory function in preterm and near-term lambs

S Yamaoka, KJ Crossley… - Journal of Applied …, 2022 - journals.physiology.org
Respiratory distress is relatively common in infants born at or near-term, particularly in
infants delivered following elective cesarean section. The pathophysiology underlying …

Influence of the chest wall on respiratory function at birth in near-term lambs

C Diedericks, KJ Crossley, IM Davies… - Journal of Applied …, 2024 - journals.physiology.org
Airway liquid is cleared into lung tissue after birth, which becomes edematous and forces the
chest wall to expand to accommodate both the cleared liquid and incoming air. This study …

External negative pressure improves lung aeration in near-term rabbit kittens at risk of developing respiratory distress

C Diedericks, KJ Crossley, D Jurkschat… - Frontiers in …, 2025 - frontiersin.org
Introduction As airway liquid is cleared into lung interstitial tissue after birth, the chest wall
must expand to accommodate this liquid and the incoming air. We examined the effect of …

Adverse respiratory patterns in near-term spontaneously breathing newborn lambs with elevated airway liquid volumes at birth

IM Davies, KJ Crossley, EV McGillick, I Nitsos… - Frontiers in …, 2024 - frontiersin.org
Introduction Recent evidence indicates that respiratory distress (RD) in near-term infants is
caused by elevated airway liquid (EL) volume at the beginning of air-breathing after birth …

Pulmonary transition at birth

IM Davies, MJ Kitchen, R Harding, AB te Pas… - The Lung, 2025 - Elsevier
Lung aeration triggers the cardiovascular transition at birth by decreasing pulmonary
vascular resistance, making it the primary underlying event that initiates the fetal to neonatal …

Optimized lung expansion ventilation modulates ventilation‐induced lung injury in preterm lambs

T Brokken, MC Hütten, DRMG Ophelders… - Pediatric …, 2024 - Wiley Online Library
Introduction Preterm infants close to viability commonly require mechanical ventilation (MV)
for respiratory distress syndrome. Despite commonly used lung‐sparing ventilation …

The development and function of the pulmonary surfactant system in health, prematurity, and genetic disease

EV McGillick, JL Morrison, EJ Parkinson-Lawrence… - The Lung, 2025 - Elsevier
The pulmonary surfactant system is uniquely positioned to meet the physical and
environmental challenges associated with the transition to air-breathing at birth and to …