Circular RNAs in Cancer: emerging functions in hallmarks, stemness, resistance and roles as potential biomarkers

M Su, Y Xiao, J Ma, Y Tang, B Tian, Y Zhang, X Li… - Molecular cancer, 2019 - Springer
Circular RNAs (circRNAs) are a class of RNA molecules with closed loops and high stability.
CircRNAs are abundantly expressed in eukaryotic organisms and exhibit both location-and …

Circular RNA in renal diseases

J Jin, H Sun, C Shi, H Yang, Y Wu, W Li… - Journal of cellular …, 2020 - Wiley Online Library
Circular RNA (circRNA) is a newly described type of non‐coding RNA. Active research is
greatly enriching the current understanding of the expression and role of circRNA, and a …

Epigenetic regulation in fibrosis progress

T Xue, X Qiu, H Liu, C Gan, Z Tan, Y Xie, Y Wang… - Pharmacological …, 2021 - Elsevier
Fibrosis, a common process of chronic inflammatory diseases, is defined as a repair
response disorder when organs undergo continuous damage, ultimately leading to scar …

The role of circular RNA CDR1as/ciRS-7 in regulating tumor microenvironment: a pan-cancer analysis

Y Zou, S Zheng, X Deng, A Yang, X Xie, H Tang, X Xie - Biomolecules, 2019 - mdpi.com
Circular RNA CDR1as/ciRS-7 functions as an oncogenic regulator in various cancers.
However, there has been a lack of systematic and comprehensive analysis to further …

Circular RNA ITCH: A novel tumor suppressor in multiple cancers

Y Li, Y Ge, L Xu, R Jia - Life sciences, 2020 - Elsevier
Circular RNAs (circRNAs) are a new type of endogenous noncoding RNAs with closed
circular structure. Emerging evidence indicates that circRNAs play crucial roles in many …

Non-coding RNA and diabetic kidney disease

H Ren, Q Wang - DNA and Cell Biology, 2021 - liebertpub.com
Diabetic kidney disease (DKD) is one of the most common chronic microvascular
complications of diabetes. In addition to the characteristic clinical manifestations of …

The emerging picture of the roles of CircRNA-CDR1as in cancer

C Jiang, X Zeng, R Shan, W Wen, J Li, J Tan… - Frontiers in cell and …, 2020 - frontiersin.org
Circular RNAs (circRNAs) are covalently closed circular structures without 5′ caps and 3′
tails, which are mainly formed from precursor mRNAs (pre-mRNAs) via back-splicing of …

[HTML][HTML] Peripheral blood circular RNA hsa_circ_0058493 as a potential novel biomarker for silicosis and idiopathic pulmonary fibrosis

Z Cheng, Y Zhang, S Wu, R Zhao, Y Yu, Y Zhou… - Ecotoxicology and …, 2022 - Elsevier
Existing studies reported that some circular RNAs (circRNAs) play vital roles in the
development of pulmonary fibrosis. However, few studies explored the biomarker potential …

New aspects of the epigenetic regulation of EMT related to pulmonary fibrosis

XC Wang, K Song, B Tu, H Sun, Y Zhou, SS Xu… - European Journal of …, 2023 - Elsevier
Pulmonary fibrosis is a chronic and progressive fibrotic disease that results in impaired gas
exchange, ventilation, and eventual death. The pro-fibrotic environment is instigated by …

[HTML][HTML] Circular RNA: A novel potential biomarker for skin diseases

X Wu, Y Xiao, J Ma, A Wang - Pharmacological research, 2020 - Elsevier
Circular RNA (circRNA) has been classified as noncoding RNA with a covalent closed
continuous loop, the 3′ and 5′ ends of which are normally joined together to increase its …