The obligate intracellular parasites Toxoplasma gondii and Plasmodium spp. invade host cells by injecting a protein complex into the membrane of the targeted cell that bridges the …
We consider a system of hardcore particles advected by a fluctuating potential energy landscape, whose dynamics is in turn affected by the particles. Earlier studies have shown …
We study the force generation by a set of parallel actin filaments growing against an elastic membrane. The elastic membrane tries to stay flat and any deformation from this flat state …
J Valiyakath, M Gopalakrishnan - Scientific Reports, 2018 - nature.com
Polymerising filaments generate force against an obstacle, as in, eg, microtubule- kinetochore interactions in the eukaryotic cell. Earlier studies of this problem have not …
Biomembranes experience out-of-equilibrium conditions in living cells. Their undulation spectra are different from those in thermal equilibrium. Here, we report on the undulation of a …
We consider a one-dimensional elastic membrane, which is pushed by growing filaments. The filaments tend to grow by creating local protrusions in the membrane and this process …
The forces that arise from the actin cortex play a crucial role in determining the membrane deformation. These include protrusive forces due to actin polymerization, pulling forces due …
Bond graphs provide an energy-based methodology for modelling complex systems in a hierarchical fashion; at the moment, the method allows biological system with both chemical …
To theoretically understand force generation properties of actin filaments, many models consider growing filaments pushing against a movable obstacle or barrier. In order to grow …