It is only recently that the full importance of nuclear factor-κB (NF-κB) signalling to cancer
development has been understood. Although much attention has focused on the upstream …

The transcription factor NF-κB has served as a standard for inducible transcription factors for
more than 20 years. The numerous stimuli that activate NF-κB, and the large number of …

Recent discoveries reveal complex interactions between skeletal muscle and the immune
system that regulate muscle regeneration. In this review, we evaluate evidence that …

The ability to sense and adjust to the environment is crucial to life. For multicellular
organisms, the ability to respond to external changes is essential not only for survival but …

The mammalian Rel/NF-κB family of transcription factors, including RelA, c-Rel, RelB, NF-
κB1 (p50 and its precursor p105), and NF-κB2 (p52 and its precursor p100), plays a central …

Nuclear factor (NF)-κB and inhibitor of NF-κB kinase (IKK) proteins regulate many
physiological processes, including the innate-and adaptive-immune responses, cell death …

The nuclear factor kB (NF-kB) comprises a family of transcription factors involved in the
regulation of a wide variety of biological responses. NF-kB plays a well-known function in …

Research on the biological function of nuclear factor-κB (NF-κB), a key mediator of inducible
transcription in the immune system, has traditionally focused on its role in the initiation of …

Abstract The NF-κB/REL family of transcription factors pivotally control the inflammatory and
immune responses, as well as other genetic programmes that are central to cell growth and …

The nuclear factor-kappa B (NF-κB) signaling pathway is a multi-component pathway that
regulates the expression of hundreds of genes that are involved in diverse and key cellular …