Updates in combined approaches of radiotherapy and immune checkpoint inhibitors for the treatment of breast cancer

KM Jungles, EA Holcomb, AN Pearson… - Frontiers in …, 2022 - frontiersin.org
Breast cancer is the most prevalent non-skin cancer diagnosed in females and developing
novel therapeutic strategies to improve patient outcomes is crucial. The immune system …

The DARC side of inflamm-aging: Duffy antigen receptor for chemokines (DARC/ACKR1) as a potential biomarker of aging, immunosenescence, and breast …

N Jinna, P Rida, T Su, Z Gong, S Yao, M LaBarge… - Cells, 2022 - mdpi.com
The proclivity of certain pre-malignant and pre-invasive breast lesions to progress while
others do not continues to perplex clinicians. Clinicians remain at a crossroads with …

Regional variation in the tumor microenvironment, immune escape and prognostic factors in breast cancer in sub-Saharan Africa

M Bauer, M Vetter, K Stückrath, M Yohannes… - Cancer immunology …, 2023 - AACR
The low overall survival rates of patients with breast cancer in sub-Saharan Africa (SSA) are
driven by regionally differing tumor biology, advanced tumor stages at diagnosis, and limited …

Molecular Differences in Pancreatic Ductal Adenocarcinomas from Black Versus White Patients

S Mandal, EA Teslow, M Huang, Y Yu… - Cancer Research …, 2025 - aacrjournals.org
Pancreatic cancer is the third leading cause of cancer-related death in the United States.
Black or African American patients have a higher incidence of pancreatic cancer compared …

Integrating genomic information with tumor-immune microenvironment in triple-negative breast cancer

D Otohinoyi, A Kuchi, J Wu, C Hicks - International Journal of …, 2022 - mdpi.com
Background: the development and progression of triple-negative breast cancer (TNBC) is
driven by somatic driver mutations and the tumor-immune microenvironment. To date, data …

There is no such a thing as a 'biological' basis for cancer disparities: A call to end misreporting of the ultimate determinants of health outcomes

D Trapani, F Girardi, S Cinieri, G Curigliano - Tumori Journal, 2024 - journals.sagepub.com
Improved strategies of cancer prevention and control have resulted in tangible benefits for
patients with cancer. Disparities in outcome have been reported as a result of inequal …

[HTML][HTML] Multiplex Imaging Reveals Novel Subcellular, Microenvironmental, and Racial Patterns of MRTFA/B Activation in Invasive Breast Cancers and Metastases

SM Wilk, K Lee, AM Gajda, M Haloul, V Macias… - bioRxiv, 2024 - ncbi.nlm.nih.gov
Breast cancer progression and metastasis involve the action of multiple transcription factors
in tumors and in the cells of the tumor microenvironment (TME) and understanding how …

Incorporating histone H2B variants into chromatin modifies chromatin accessibility to induce epithelial to mesenchymal transition in breast cancer

H Dhahri, KH Lau, WN Saintilnord, E Lopes… - bioRxiv, 2024 - biorxiv.org
Histones scaffold genomic DNA and regulate access to the transcriptional machinery.
However, naturally occurring histone variants can alter histone-DNA interactions, DNA and …

[HTML][HTML] Durable Response to Programmed Death 1-Directed Antibodies in a Hypermutated Triple-Negative Breast Cancer: A Case Report

E Platteter, G Wulf - Case Reports in Oncology, 2024 - karger.com
Introduction: The advent of immune checkpoint inhibitors marks significant progress in the
evolution of cancer treatment. Recent clinical trials have demonstrated the success of …

[PDF][PDF] Review on Breast Cancer in Iraq Women

MMA Jassim, BJ Hamad, MH Hussein - University of Thi-Qar Journal of …, 2022 - iasj.net
Abstract:" breast cancer" which is common type of carcinogenesis in females, surpassing
even bronchogenic cancer" accounting for approximately one-third of the registered female …