Peptides are fragments of proteins that carry out biological functions. They act as signaling
entities via all domains of life and interfere with protein-protein interactions, which are …

Cyclic dipeptides, also know as diketopiperazines (DKP), the simplest cyclic forms of
peptides widespread in nature, are unsurpassed in their structural and bio-functional …

Invarioms are aspherical atomic scattering factors that enable structure refinement of more
accurate and more precise geometries than refinements with the conventional independent …

Short peptides have great potential as safe and effective anticancer drug leads. Herein, the
influence of short cyclic peptides containing the Pro-Pro-Phe-Phe sequence on patient …

The tetrazole moiety is a versatile scaffold in medicinal chemistry due to its specific structure
and essential roles in biosciences. Here, a supramolecular behavior of newly synthesized …

Considering the increasing importance of cyclopropyl-containing peptide-derived
compounds in the pharmaceutical industry, herein, we report the crystal engineering of a …

Proline is a unique, endogenous amino acid, prevalent in proteins and essential for living
organisms. It is appreciated as a tecton for the rational design of new bio-active substances …

Targeting the polyamine biosynthetic pathway by inhibiting ornithine decarboxylase (ODC)
is a powerful approach in the fight against diverse viruses, including SARS-CoV-2 …

The title compound, N-benzoyl-2′-hydroxy-3-methylisovaline, representing synthon
polymorphism, can be interesting inter alia from the point of view of modern supramolecular …

The crystal structures of captopril {systematic name:(2S)-1-[(2S)-2-methyl-3-
sulfanylpropanoyl] pyrrolidine-2-carboxylic acid}, C9H15NO3S,(1), and its dimer disulfide …