Cyclophosphamide (Cy) is a prodrug that is mainly bioactivated by cytochrome P450 (CYP)
2B6 enzyme. Several other enzymes are also involved in its bioactivation and affect its …

Busulfan and cyclophosphamide (BuCy) is a frequently used myeloablative conditioning
regimen for allogeneic hematopoietic cell transplantation (allo-HCT). Theoretical …

Fanconi anemia is the most common inherited bone marrow failure syndrome, and
hematopoietic stem cell transplantation (HSCT) is the only curative option. Post-transplant …

Busulfan (Bu) is widely used in conditioning regimens before allogeneic hematopoietic cell
transplantation, with variable metabolism due to interindividual differences of …

Objective: to analyze the factors associated with the failure of Hematopoietic Stem Cell
Transplantation (HSCT) in patients undergoing Hematopoietic Stem Cell Retransplantation …

Sinusoidal obstructive syndrome (SOS), or veno-occlusive disease, of the liver has been
recognized as a complex, life-threatening complication in the posthematopoietic stem cell …

Despite advances in understanding the biology of mature T and natural killer (NK)/T cell
neoplasia, current therapies, even the most innovative ones, are still far from ensuring its …

Hepatic sinusoidal obstruction syndrome (SOS) is a complication related to endothelial
damage that appears early after hematopoietic stem cell transplantation (SCT). Hepatic SOS …

Busulfan (Bu) combined with cyclophosphamide (Cy) is commonly used as a myeloablative
conditioning regimen for allogeneic hematopoietic cell transplantation (allo-HCT). There is …

Objetivo: analizar los factores asociados con el fracaso del Trasplante de Células Madre
Hematopoyéticas (TCMH) en pacientes sometidos al Retrasplante de Células Madre …