Enteroviruses: epidemic potential, challenges and opportunities with vaccines

M Jartti, M Flodström-Tullberg… - Journal of Biomedical …, 2024 - Springer
Enteroviruses (EVs) are the most prevalent viruses in humans. EVs can cause a range of
acute symptoms, from mild common colds to severe systemic infections such as meningitis …

The Picornaviridae Family: Knowledge Gaps, Animal Models, Countermeasures, and Prototype Pathogens

R Andino, K Kirkegaard, A Macadam… - The Journal of …, 2023 - academic.oup.com
Picornaviruses are nonenveloped particles with a single-stranded RNA genome of positive
polarity. This virus family includes poliovirus, hepatitis A virus, rhinoviruses, and …

Comprehensive profiling of neutralizing polyclonal sera targeting coxsackievirus B3

B Álvarez-Rodríguez, J Buceta, R Geller - Nature Communications, 2023 - nature.com
Despite their fundamental role in resolving viral infections, our understanding of how
polyclonal neutralizing antibody responses target non-enveloped viruses remains limited …

Global age-stratified seroprevalence of enterovirus D68: a systematic literature review

D Jorgensen, NC Grassly, M Pons-Salort - The Lancet Microbe, 2024 - thelancet.com
Summary Enterovirus D68 (EV-D68), first isolated in 1962, emerged in 2014, causing
outbreaks of severe respiratory infections and acute flaccid myelitis. In this systematic …

Assessment of twelve echovirus virus-neutralisation assays in Europe: recommendations for harmonisation of non-polio enterovirus sero-surveillance studies

K Couderé, KSM Benschop, G Koen… - Journal of General …, 2024 - microbiologyresearch.org
Non-polio enteroviruses (NPEV) cause significant disease worldwide. Population-based
sero-surveillance, by measuring antibodies against specific NPEV types, provides additional …

Enterovirus virus-like-particle and inactivated poliovirus vaccines do not elicit substantive cross-reactive antibody responses

DL Moss, AC Paine, PW Krug, M Kanekiyo… - Plos …, 2024 - journals.plos.org
Human enteroviruses are the most common human pathogen with over 300 distinct
genotypes. Previous work with poliovirus has suggested that it is possible to generate …

[HTML][HTML] Multimodal Surveillance Model for Enterovirus D68 Respiratory Disease and Acute Flaccid Myelitis among Children in Colorado, USA, 2022

K Messacar, S Matzinger, K Berg… - Emerging Infectious …, 2024 - ncbi.nlm.nih.gov
Surveillance for emerging pathogens is critical for developing early warning systems to
guide preparedness efforts for future outbreaks of associated disease. To better define the …

Animal models of enterovirus D68 infection and disease

MS Vermillion, J Dearing, Y Zhang, DR Adney… - Journal of …, 2022 - Am Soc Microbiol
ABSTRACT Human enterovirus D68 (EV-D68) is a globally reemerging respiratory
pathogen that is associated with the development of acute flaccid myelitis (AFM) in children …

Enterovirus-D68–a reemerging non-polio enterovirus that causes severe respiratory and neurological disease in children

CS Grizer, K Messacar, JJ Mattapallil - Frontiers in Virology, 2024 - frontiersin.org
The past decade has seen the global reemergence and rapid spread of enterovirus D68 (EV-
D68), a respiratory pathogen that causes severe respiratory illness and paralysis in children …

Progress in etiological diagnosis of viral meningitis

H Xu, P Chen, S Guo, X Shen, Y Lu - Frontiers in Neurology, 2023 - frontiersin.org
In recent years, with the rapid development of molecular biology techniques such as
polymerase chain reaction and molecular biochip, the etiological diagnosis of viral …