Changing epidemiology of hepatocellular carcinoma in Asia

C Zhang, Y Cheng, S Zhang, J Fan, Q Gao - Liver International, 2022 - Wiley Online Library
Liver cancer is the fifth most common cancer and the second leading cause of malignant
death in Asia, and Asia reports 72.5% of the world's cases in 2020. As the most common …

Treatment failure with DAA therapy: Importance of resistance

C Sarrazin - Journal of Hepatology, 2021 - Elsevier
Viral resistance is a major reason for virological failure in patients being treated with direct-
acting antivirals (DAAs) for chronic HCV infection. However, the importance of viral …

[PDF][PDF] Hepatitis C guidance 2019 update: American Association for the Study of Liver Diseases–Infectious Diseases Society of America recommendations for testing …

MG Ghany, TR Morgan… - …, 2020 - Wiley Online Library
HCV infection, risk-based screening failed to identify the majority of individuals with HCV
infection due to both clinician and patient barriers.(9-12) Analysis of the 2003-2010 National …

EASL recommendations on treatment of hepatitis C: final update of the series☆

JM Pawlotsky, F Negro, A Aghemo, M Berenguer… - Journal of …, 2020 - Elsevier
Hepatitis C virus (HCV) infection is a major cause of chronic liver disease, with
approximately 71 million chronically infected individuals worldwide. Clinical care for patients …

[HTML][HTML] 2020 Taiwan consensus statement on the management of hepatitis C: part (I) general population

ML Yu, PJ Chen, CY Dai, TH Hu, CF Huang… - Journal of the Formosan …, 2020 - Elsevier
Hepatitis C virus (HCV) infection remains a major public health issue with high prevalence in
Taiwan. Recently, the advent of direct-acting antiviral (DAA) agents, with higher efficacy …

Resistance mechanisms to osimertinib in EGFR-mutated advanced non-small-cell lung cancer: a multicentric retrospective French study

C Mehlman, J Cadranel, G Rousseau-Bussac… - Lung Cancer, 2019 - Elsevier
Objectives The understanding of histo-molecular mechanisms associated with resistance to
osimertinib is a critical step to define the optimal treatment strategy in advanced EGFR …

[HTML][HTML] Real-world effectiveness of voxilaprevir/velpatasvir/sofosbuvir in patients following DAA failure

C Graf, R D'Ambrosio, E Degasperi, S Paolucci… - JHEP Reports, 2024 - Elsevier
Background & Aims Voxilaprevir/velpatasvir/sofosbuvir (VOX/VEL/SOF) is highly effective for
re-treatment of direct-acting antiviral (DAA)-experienced patients with chronic HCV infection …

[HTML][HTML] Non-epidemic HCV genotypes in low-and middle-income countries and the risk of resistance to current direct-acting antiviral regimens

R Shah, L Ahovegbe, M Niebel, J Shepherd… - Journal of …, 2021 - Elsevier
The hepatitis C virus (HCV) is an extremely diverse virus, subtypes of which are distributed
variably around the world. Viral genotypes may be divided into epidemic subtypes; those …

Targeting chronic liver diseases: Molecular markers, drug delivery strategies and future perspectives

J Unagolla, S Das, R Flanagan, M Oehler… - International Journal of …, 2024 - Elsevier
Chronic liver inflammation, a pervasive global health issue, results in millions of annual
deaths due to its progression from fibrosis to the more severe forms of cirrhosis and …

Screening for hepatitis C virus infection in adolescents and adults: updated evidence report and systematic review for the US Preventive Services Task Force

R Chou, T Dana, R Fu, B Zakher, J Wagner, S Ramirez… - JAMA, 2020 - jamanetwork.com
Importance A 2013 review for the US Preventive Services Task Force (USPSTF) of hepatitis
C virus (HCV) screening found interferon-based antiviral therapy associated with increased …