3D engineering of diseased blood vessels for integrative in vitro–in silico mechanobiology study

W Park, JS Lee, MJ Choi, WW Cho, SH Lee… - …, 2024 - iopscience.iop.org
Vascular diseases are complex conditions orchestrated by multiple factors, including cellular
components, biochemical stimuli, and mechanical forces. Despite the advancement of …

Learning whole heart mesh generation from patient images for computational simulations

F Kong, SC Shadden - IEEE Transactions on Medical Imaging, 2022 - ieeexplore.ieee.org
Patient-specific cardiac modeling combines geometries of the heart derived from medical
images and biophysical simulations to predict various aspects of cardiac function. However …

Calibration of patient-specific boundary conditions for coupled CFD models of the aorta derived from 4D Flow-MRI

SMD Black, C Maclean, P Hall Barrientos… - … in Bioengineering and …, 2023 - frontiersin.org
Introduction: Patient-specific computational fluid dynamics (CFD) models permit analysis of
complex intra-aortic hemodynamics in patients with aortic dissection (AD), where vessel …

CT-based simulation of left ventricular hemodynamics: a pilot study in mitral regurgitation and left ventricle aneurysm patients

L Obermeier, K Vellguth, A Schlief, L Tautz… - Frontiers in …, 2022 - frontiersin.org
Background Cardiac CT (CCT) is well suited for a detailed analysis of heart structures due to
its high spatial resolution, but in contrast to MRI and echocardiography, CCT does not allow …

An image-based approach for the estimation of arterial local stiffness in vivo

S Celi, E Gasparotti, K Capellini, F Bardi… - … in Bioengineering and …, 2023 - frontiersin.org
The analysis of mechanobiology of arterial tissues remains an important topic of research for
cardiovascular pathologies evaluation. In the current state of the art, the gold standard to …

Uncertainty quantification in the in vivo image-based estimation of local elastic properties of vascular walls

BM Fanni, MN Antonuccio, A Pizzuto, S Berti… - Journal of …, 2023 - mdpi.com
Introduction: Patient-specific computational models are a powerful tool for planning
cardiovascular interventions. However, the in vivo patient-specific mechanical properties of …

Fabrication of deformable patient-specific AAA models by material casting techniques

MN Antonuccio, E Gasparotti, F Bardi… - Frontiers in …, 2023 - frontiersin.org
Background Abdominal Aortic Aneurysm (AAA) is a balloon-like dilatation that can be life-
threatening if not treated. Fabricating patient-specific AAA models can be beneficial for in …

Fluid dynamic model for extracorporeal membrane oxygenation support and perfusion in cardiogenic shock

E Vignali, E Gasparotti, D Haxhiademi, S Celi - Physics of Fluids, 2023 - pubs.aip.org
The venoarterial extracorporeal membrane oxygenation (VA-ECMO) is a widely adopted
procedure to provide oxygenated blood support in patients who underwent cardiac shock …

Image-based modelling and numerical simulations of the Cardioband® procedure for mitral valve regurgitation repair

E Gasparotti, E Vignali, M Mariani, S Berti… - Computer Methods in …, 2022 - Elsevier
Mitral regurgitation is one of the most common valvular heart diseases and is mainly caused
by dilatation of the valvular annulus as a result of remodelling of the left ventricle …

Quantitative Criteria for the Degree of Pathological Remodeling of the Aortic Duct

E Talygin, A Gorodkov, T Tibua, L Bockeria - Mathematics, 2022 - mdpi.com
Analysis of the properties of the aorta was carried out by numerous researchers using
several parameters. However, the general laws of change in the dynamic geometry of the …