[HTML][HTML] An update on oral drug delivery via intestinal lymphatic transport

Z Zhang, Y Lu, J Qi, W Wu - Acta Pharmaceutica Sinica B, 2021 - Elsevier
Orally administered drug entities have to survive the harsh gastrointestinal environment,
penetrate the enteric epithelia and circumvent hepatic metabolism before reaching the …

Progress and prospects of polysaccharide-based nanocarriers for oral delivery of proteins/peptides

H Yuan, C Guo, L Liu, L Zhao, Y Zhang, T Yin… - Carbohydrate …, 2023 - Elsevier
The oral route has long been recognized as the most preferred route for drug delivery as it
offers high patient compliance and requires minimal expertise. Unlike small molecule drugs …

RoboCap: Robotic mucus-clearing capsule for enhanced drug delivery in the gastrointestinal tract

SS Srinivasan, A Alshareef, AV Hwang, Z Kang… - Science robotics, 2022 - science.org
Oral drug delivery of proteins is limited by the degradative environment of the
gastrointestinal tract and poor absorption, requiring parenteral administration of these drugs …

Quercetin liposomes ameliorate streptozotocin-induced diabetic nephropathy in diabetic rats

L Tang, K Li, Y Zhang, H Li, A Li, Y Xu, B Wei - Scientific reports, 2020 - nature.com
The effects of quercetin liposomes (Q-PEGL) on streptozotocin (STZ)-induced diabetic
nephropathy (DN) was investigated in rats. Male Sprague Dawley rats were used to …

Oral insulin delivery: Barriers, strategies, and formulation approaches: A comprehensive review

SS Shetty, P Halagali, AP Johnson… - International Journal of …, 2023 - Elsevier
Diabetes Mellitus is characterized by a hyperglycemic condition which can either be caused
by the destruction of the beta cells or by the resistance developed against insulin in the cells …

TPGS-chitosan cross-linked targeted nanoparticles for effective brain cancer therapy

P Agrawal, RP Singh, L Kumari, G Sharma… - Materials science and …, 2017 - Elsevier
Brain cancer, up-regulated with transferrin receptor led to concept of transferrin receptor
targeted anticancer therapeutics. Docetaxel loaded d-α-tocopherol polyethylene glycol 1000 …

Synthesis of CSK-DEX-PLGA nanoparticles for the oral delivery of exenatide to improve its mucus penetration and intestinal absorption

Y Song, Y Shi, L Zhang, H Hu, C Zhang… - Molecular …, 2019 - ACS Publications
The oral absorption of exenatide, a drug for type 2 diabetes treatment, can be improved by
using nanoparticles (NPs) for its delivery. To improve the mucus penetration and intestinal …

A review on emerging role of multifunctional carbon nanotubes as an armament in cancer therapy, imaging and biosensing

PS Chary, R Bhawale, R Vasave, N Rajana… - Journal of Drug Delivery …, 2023 - Elsevier
The use of traditional chemotherapy to treat cancer is often limited by the toxic side effects of
anti-cancer drugs on the body. Additionally, there are major challenges in the form of higher …

RGD-TPGS decorated theranostic liposomes for brain targeted delivery

RP Singh, G Sharma, L Kumari, B Koch, S Singh… - Colloids and surfaces B …, 2016 - Elsevier
The aim of this work was to formulate RGD-TPGS decorated theranostic liposomes, which
contain both docetaxel (DTX) and quantum dots (QDs) for brain cancer imaging and therapy …

Chitosan-folate decorated carbon nanotubes for site specific lung cancer delivery

RP Singh, G Sharma, S Singh, S Bharti… - Materials Science and …, 2017 - Elsevier
The aim of this work was to formulate chitosan-folate conjugated multi-walled carbon
nanotubes for the lung cancer targeted delivery of docetaxel. The chitosan-folate conjugate …