Abstract 4 H‐pyrido [1, 2‐a] pyrimidin‐4‐one and their derivatives are highly bioactive and
multipurpose heterocyclic motifs, having application in drugs, natural products …

Kynurenic acid (KYNA) is an endogenous neuroprotective agent of increasing importance.
Several derivatives have already been synthesized, bearing an abundance of functional …

An environmentally friendly protocol for the synthesis of C3‐selenylated 4H‐pyrido [1, 2‐a]
pyrimidin‐4‐ones was developed via the electrochemical oxidation, iodide‐catalyzed …

Various multi-substituted pyrido [1, 2-a] pyrimidin-4-ones were synthesized via a one-pot
tandem CuI-catalyzed C–N bond formation/intramolecular amidation reaction at 130° C in …

A simple one‐pot protocol for the synthesis of benzylpyrazolyl coumarin and pyrano [2, 3‐c]
pyrazole derivatives in the presence of potassium dihydrogen phosphate (KH2PO4) has …

Late-stage functionalization of pyrido [1, 2-a] pyrimidin-4-one at pyrimidine ring structure is
crucial to design pharmaceuticals, agrochemicals and materials for sustainable …

氨基吡啶是一类重要的合成子, 具有独特的双亲核结构, 可与酮, 醛, 酸, 多官能团酯类以及卤代
芳烃等化合物反应, 以构建五元, 六元含氮稠杂环. 近年来, 基于2-氨基吡啶的成环反应倍受关注 …

Aminopyridine is a significant synthetic synthon, with unique dual nucleophilic structure. It
can react with ketones, aldehydes, acids, multifunctional esters, halogenated aromatics and …

The Conrad–Limpach procedure used in the synthesis of the ethyl ester of KYNA and its
alkyl-, aryl-, and halogen-substituted derivatives has been optimized using two steps:(i) …

[504‐29‐0] C5H6N2 (MW 94.117) InChI= 1S/C5H6N2/c6‐5‐3‐1‐2‐4‐7‐5/h1‐4H,(H2, 6, 7)
InChIKey= ICSNLGPSRYBMBD‐UHFFFAOYSA‐N Alternative Names: 2‐pyridinamine, 2 …