Class III receptor tyrosine kinases in acute leukemia–biological functions and modern laboratory analysis

R Berenstein - Biomarker insights, 2015 - journals.sagepub.com
Acute myeloid leukemia (AML) is a complex disease caused by deregulation of multiple
signaling pathways. Mutations in class III receptor tyrosine kinases (RTKs) have been …

Content analysis of informed consent for whole genome sequencing offered by direct‐to‐consumer genetic testing companies

E Niemiec, P Borry, W Pinxten, HC Howard - Human mutation, 2016 - Wiley Online Library
Whole exome sequencing (WES) and whole genome sequencing (WGS) have become
increasingly available in the research and clinical settings and are now also being offered …

Genomic data integration in chronic lymphocytic leukemia

JL Fernández‐Martínez… - The journal of gene …, 2017 - Wiley Online Library
Background B‐cell chronic lymphocytic leukemia (CLL) is a heterogeneous disease and the
most common adult leukemia in western countries. IgVH mutational status distinguishes two …

XPD gene polymorphisms and the effects of induction chemotherapy in cytogenetically normal de novo acute myeloid leukemia patients

MA El-Tokhy, NA Hussein, AML Bedewy… - Hematology, 2014 - Taylor & Francis
Background Cytogenetically normal acute myeloid leukemia (AML) represents nearly half of
newly diagnosed de novo AML cases. XPD is one of the DNA repair proteins, whose genetic …

Prognostic value of bone marrow MUC4 expression in acute myeloid leukaemia

AS Abdelhady, FF Abdel Hamid… - British journal of …, 2020 - Taylor & Francis
Background: Aberrant expression of mucin-4 (MUC4) is present in a variety of solid cancers,
but the expression pattern of MUC4 and its clinical relevance in acute myeloid leukaemia …

Identification of somatic mutations using whole-exome sequencing in Korean patients with acute myeloid leukemia

SG Heo, Y Koh, JK Kim, J Jung, HL Kim, SS Yoon… - BMC Medical …, 2017 - Springer
Background Acute myeloid leukemia (AML) is a biologically and clinically heterogeneous
cancer of the bone marrow that is characterized by the rapid growth of abnormal myeloid …

Caractérisation moléculaire d'un récent modèle d'étude de la leucémie myéloïde aigüe à caryotype normal: la lignée cellulaire CG-SH

G Gosse - 2014 - papyrus.bib.umontreal.ca
La leucémie myéloïde aigüe (LMA) est la forme de leucémie la plus fréquente chez l'adulte
au Canada. Bien que de nombreux réarrangements chromosomiques récurrents aient été …