[HTML][HTML] Post-operative adhesions: a comprehensive review of mechanisms

A Fatehi Hassanabad, AN Zarzycki, K Jeon, JF Deniset… - Biomedicines, 2021 - mdpi.com
Post-surgical adhesions are common in almost all surgical areas and are associated with
significant rates of morbidity, mortality, and increased healthcare costs, especially when a …

[HTML][HTML] TGF-beta signal transduction: biology, function and therapy for diseases

Y Tie, F Tang, D Peng, Y Zhang, H Shi - Molecular biomedicine, 2022 - Springer
The transforming growth factor beta (TGF-β) is a crucial cytokine that get increasing concern
in recent years to treat human diseases. This signal controls multiple cellular responses …

[HTML][HTML] Prospects and challenges of electrospun cell and drug delivery vehicles to correct urethral stricture

S Farzamfar, E Elia, S Chabaud, M Naji… - International Journal of …, 2022 - mdpi.com
Current therapeutic modalities to treat urethral strictures are associated with several
challenges and shortcomings. Therefore, significant strides have been made to develop …

Evaluation of the effects of peritoneal lavage with Rosmarinus officinalis extract against the prevention of postsurgical-induced peritoneal adhesion

Y Roohbakhsh, VB Rahimi, S Silakhori… - Planta …, 2020 - thieme-connect.com
Postoperative adhesions are regarded as the major complication following abdominal
surgery. Rosmarinus officinalis has shown antioxidative and anti-inflammatory effects …

[HTML][HTML] Herbal formula Jiawei Xiaochengqi decoction prevents postoperative abdominal adhesion in a rat model through inhibition of CXCL2-CXCR2 pathway

W Liu, F Wu, X Bi, L Hou, C Wang, Y Li, Z Zeng, C Xia… - Phytomedicine, 2023 - Elsevier
Background Postoperative abdominal adhesion (PAA) is the most common complication
after abdominal surgeries, which can lead to intestinal obstruction, chronic abdominal pain …

Regenerative medicine therapies for prevention of abdominal adhesions: A scoping review

SP Carmichael II, J Shin, JW Vaughan… - Journal of Surgical …, 2022 - Elsevier
Introduction Globally, abdominal adhesions constitute a significant burden of morbidity and
mortality. They represent the commonest complication of abdominal operations with a …

EW‐7197 prevents ulcerative colitis‐associated fibrosis and inflammation

MM Binabaj, F Asgharzadeh, A Avan… - Journal of cellular …, 2019 - Wiley Online Library
EW‐7197 is a transforming growth factor‐β type I receptor kinase inhibitor with potential anti‐
inflammatory and antifibrotic properties. Here, we investigate the potential therapeutic effects …

[HTML][HTML] Sirolimus-eluting cobalt–chrome alloy stent suppresses stent-induced tissue hyperplasia in a porcine Eustachian tube model

JM Kang, SH Kim, YJ Choi, Y Park, DS Ryu… - Scientific Reports, 2022 - nature.com
Various preclinical studies with developed Eustachian tube (ET) stents are in progress but
have not yet been clinically applied. ET stent is limited by stent-induced tissue hyperplasia in …

Sodium aescinate significantly suppress postoperative peritoneal adhesion by inhibiting the RhoA/ROCK signaling pathway

W Liu, F Qin, F Wu, H Feng, Q Yang, L Hou, M Peng… - Phytomedicine, 2020 - Elsevier
Background Although mechanical barriers and modern surgical techniques have been
developed to prevent postoperative adhesion formation, high incidence of adhesions still …

[HTML][HTML] Salvia miltiorrhiza hydroalcoholic extract inhibits postoperative peritoneal adhesions in rats

A Raisi, O Dezfoulian, F Davoodi, S Taheri… - … Medicine and Therapies, 2021 - Springer
Background One of the most prevalent postoperative complications is believed to be intra-
abdominal peritoneal adhesions, which is followed by several complications. Several …