Unraveling the complex genetics of neural tube defects: From biological models to human genomics and back
Neural tube defects (NTDs) are a classic example of preventable birth defects for which
there is a proven‐effective intervention, folic acid (FA); however, further methods of …
there is a proven‐effective intervention, folic acid (FA); however, further methods of …
Multimodal AI/ML for discovering novel biomarkers and predicting disease using multi-omics profiles of patients with cardiovascular diseases
W DeGroat, H Abdelhalim, E Peker, N Sheth… - Scientific Reports, 2024 - nature.com
Cardiovascular diseases (CVDs) are complex, multifactorial conditions that require
personalized assessment and treatment. Advancements in multi-omics technologies …
personalized assessment and treatment. Advancements in multi-omics technologies …
Mutations in Hsp90 cochaperones result in a wide variety of human disorders
JL Johnson - Frontiers in Molecular Biosciences, 2021 - frontiersin.org
The Hsp90 molecular chaperone, along with a set of approximately 50 cochaperones,
mediates the folding and activation of hundreds of cellular proteins in an ATP-dependent …
mediates the folding and activation of hundreds of cellular proteins in an ATP-dependent …
FKBP38 suppresses endometrial cancer cell proliferation and metastasis by inhibiting the mTOR pathway
Y Yan, S Wang, Z Zhang, M Tang, AZ Zhao, Z Li… - Archives of Biochemistry …, 2024 - Elsevier
Endometrial cancer (EC) is a common gynecological malignancy, and advanced-stage or
recurrent EC is associated with a high mortality rate owing to the ineffectiveness of currently …
recurrent EC is associated with a high mortality rate owing to the ineffectiveness of currently …
Prevalence and disparities in sexual and reproductive health of women of reproductive age (20–49 years) in China: A national cross-sectional study
T Tian, R Yang, Y Fu, Z Zhou, W Qian… - Journal of Global …, 2024 - pmc.ncbi.nlm.nih.gov
Background Ensuring women's sexual and reproductive health (SRH) is a fundamental
human right and key to 2030 agenda of the UN Sustainable Development Goals (SDGs), yet …
human right and key to 2030 agenda of the UN Sustainable Development Goals (SDGs), yet …
Identification of the key regulators of spina bifida through graph-theoretical approach
N Tamkeen, SY AlOmar, SAM Alqahtani… - Frontiers in …, 2021 - frontiersin.org
Spina Bifida (SB) is a congenital spinal cord malformation. Efforts to discern the key
regulators (KRs) of the SB protein-protein interaction (PPI) network are requisite for …
regulators (KRs) of the SB protein-protein interaction (PPI) network are requisite for …
New Insights into Neural Tube Closure: Folic Acid Non-Responsive Neural Tube Defects.
REN Wen-Bin, LI Jian-Ting… - Chinese Journal of …, 2024 - search.ebscohost.com
Neural tube defects (NTDs) are common, severe, and complicated congenital malformations
that are the result of the interaction and interplay of genetic, nutritional, and environmental …
that are the result of the interaction and interplay of genetic, nutritional, and environmental …