Polymeric mixed micelles as nanomedicines: Achievements and perspectives

M Cagel, FC Tesan, E Bernabeu, MJ Salgueiro… - European Journal of …, 2017 - Elsevier
During the past few decades, polymeric micelles have raised special attention as novel
nano-sized drug delivery systems for optimizing the treatment and diagnosis of numerous …

Polymeric micelles as drug delivery vehicles

Z Ahmad, A Shah, M Siddiq, HB Kraatz - Rsc Advances, 2014 - pubs.rsc.org
Though much progress has been made in drug delivery systems, the design of a suitable
carrier for the delivery of hydrophobic drugs is still a major challenge for researchers. The …

Polymeric micelles and alternative nanonized delivery vehicles for poorly soluble drugs

Y Lu, K Park - International journal of pharmaceutics, 2013 - Elsevier
Poorly soluble drugs often encounter low bioavailability and erratic absorption patterns in
the clinical setting. Due to the rising number of compounds having solubility issues, finding …

Polymeric micelles in anticancer therapy: targeting, imaging and triggered release

C Oerlemans, W Bult, M Bos, G Storm… - Pharmaceutical …, 2010 - Springer
Micelles are colloidal particles with a size around 5–100 nm which are currently under
investigation as carriers for hydrophobic drugs in anticancer therapy. Currently, five micellar …

The dawning era of polymer therapeutics

R Duncan - Nature reviews Drug discovery, 2003 - nature.com
As we enter the twenty-first century, research at the interface of polymer chemistry and the
biomedical sciences has given rise to the first nano-sized (5–100 nm) polymer-based …

Polymeric micelles drug delivery system in oncology

J Gong, M Chen, Y Zheng, S Wang, Y Wang - Journal of Controlled …, 2012 - Elsevier
Polymeric micelles (PM) system, as an efficient drug carrier, has received growing scientific
attention in recent years owing to its solubilization, selective targeting, P-glycoprotein …

Nanomedicine-based delivery strategies for breast cancer treatment and management

P Tagde, A Najda, K Nagpal, GT Kulkarni… - International journal of …, 2022 - mdpi.com
Breast cancer is one of the most common types of cancer among women globally. It is
caused by mutations in the estrogen/progesterone receptors and conventional treatment …

Pluronic® block copolymers as novel polymer therapeutics for drug and gene delivery

AV Kabanov, EV Batrakova, VY Alakhov - Journal of controlled release, 2002 - Elsevier
Pluronic® block copolymers are found to be an efficient drug delivery system with multiple
effects. The incorporation of drugs into the core of the micelles formed by Pluronic® results …

Pluronic block copolymers: evolution of drug delivery concept from inert nanocarriers to biological response modifiers

EV Batrakova, AV Kabanov - Journal of controlled release, 2008 - Elsevier
Polymer nanomaterials have sparked a considerable interest as vehicles used for diagnostic
and therapeutic agents; research in nanomedicine has not only become a frontier movement …

P-glycoprotein inhibition as a therapeutic approach for overcoming multidrug resistance in cancer: current status and future perspectives

Z Binkhathlan, A Lavasanifar - Current cancer drug targets, 2013 - ingentaconnect.com
One of the major causes of failure in cancer chemotherapy is multidrug resistance (MDR),
where cancer cells simultaneously become resistant to different anticancer drugs. Over …