Inflammasomes are intracellular complexes involved in the innate immunity that convert
proIL‐1β and proIL‐18 to mature forms and initiate pyroptosis via cleaving procaspase‐1 …

Calcium channel blockers (CCBs) were developed as vasodilators, and their use in
cardiovascular disease treatment remains largely based on that mechanism of action. More …

Small angle X-ray diffraction was used to examine arterial smooth muscle cell (SMC) plasma
membranes isolated from control and cholesterol-fed (2%) atherosclerotic rabbits. A …

Coronary artery disease (CAD) is the consequence of atherosclerosis, a vascular disorder
that is the leading cause of death and disability throughout much of the developed world …

Calcium channel blockers (CCBs) represent a chemically and pharmacologically diverse
group of agents that are widely used for the treatment of hypertension and angina. A small …

Cumulative evidence reveals that diabetes is a condition in which cell Ca 2+ homeostasis is
impaired. Defects in cell Ca 2+ regulation were found in erythrocytes, cardiac muscle …

Background. As a multifaceted disease, atherosclerosis is often characterized by the
formation and accumulation of plaque anchored to the inner wall of the arteries and causes …

Objective The objective of this study was to assess the effect of amlodipine-atorvastatin
combination on plasma interleukin-6 (IL-6), tumor necrosis factor-α (TNF-α) and insulin …

Calcium channel blockers (CCBs) are important in the management of hypertension and
limit restenosis. Although CCB efficacy could derive from decreased blood pressure, other …

In atherosclerosis lipoproteins stimulate the innate immune response, leading to the release
of inflammatory cytokines and chemokines. Hypercholesterolemia may activate the …