A systematic review on fluoride-induced epigenetic toxicity in mammals

S Balasubramanian, E Perumal - Critical Reviews in Toxicology, 2022 - Taylor & Francis
Fluoride, one of the global groundwater contaminants, is ubiquitous in our day-to-day life
from various natural and anthropogenic sources. Numerous in vitro, in vivo, and …

Independent phenotypic plasticity axes define distinct obesity sub-types

CH Yang, L Fagnocchi, S Apostle, V Wegert… - Nature …, 2022 - nature.com
Studies in genetically 'identical'individuals indicate that as much as 50% of complex trait
variation cannot be traced to genetics or to the environment. The mechanisms that generate …

Neuronatin promotes SERCA uncoupling and its expression is altered in skeletal muscles of high‐fat diet‐fed mice

JL Braun, ACT Teng, MS Geromella, CR Ryan… - FEBS …, 2021 - Wiley Online Library
Neuronatin (NNAT) is a transmembrane protein in the endoplasmic reticulum involved in
metabolic regulation. It shares sequence homology with sarcolipin (SLN), which negatively …

Identification of adipose tissue transcriptomic memory of anorexia nervosa

RC Zapata, CA Nasamran, DR Chilin-Fuentes… - Molecular …, 2023 - Springer
Background Anorexia nervosa (AN) is a complex debilitating disease characterized by
intense fear of weight gain and excessive exercise. It is the deadliest of any psychiatric …

Low-dose lithium supplementation promotes adipose tissue browning and sarco (endo) plasmic reticulum Ca2+ ATPase uncoupling in muscle

MS Geromella, CR Ryan, JL Braun, MS Finch… - Journal of Biological …, 2022 - ASBMB
Sarco (endo) plasmic reticulum Ca 2+-ATPase (SERCA) uncoupling in skeletal muscle and
mitochondrial uncoupling via uncoupling protein 1 (UCP1) in brown/beige adipose tissue …

Characterizing SERCA function in murine skeletal muscles after 35–37 days of spaceflight

JL Braun, MS Geromella, SI Hamstra… - International journal of …, 2021 - mdpi.com
It is well established that microgravity exposure causes significant muscle weakness and
atrophy via muscle unloading. On Earth, muscle unloading leads to a disproportionate loss …

[HTML][HTML] Integrating genome-wide association study and pathway analysis reveals physiological aspects affecting heifer early calving defined at different ages in …

LFM Mota, AB Carvajal, PA Bernardes, ME Buzanskas… - Genomics, 2022 - Elsevier
Heifer early calving (HC) plays a key role in beef cattle herds' economic sustainability and
profitability by reducing production costs and generation intervals. However, the genetic …

Allulose attenuated age‐associated sarcopenia via regulating IGF‐1 and myostatin in aged mice

JE Kim, EY Kwon, Y Han - Molecular Nutrition & Food …, 2022 - Wiley Online Library
Scope Allulose is shown to increase the muscle weight in diet‐induced obese mice.
However, there are no studies on the effects of allulose in age‐associated sarcopenia. This …

[HTML][HTML] Regulation of beige adipocyte thermogenesis by the cold-repressed ER protein NNAT

KM Choi, CY Ko, SM An, SH Cho, DJ Rowland… - Molecular …, 2023 - Elsevier
Objective Cold stimuli trigger the conversion of white adipose tissue into beige adipose
tissue, which is capable of non-shivering thermogenesis. However, what process drives this …

[HTML][HTML] Perlecan (HSPG2) promotes structural, contractile, and metabolic development of human cardiomyocytes

BB Johnson, MV Cosson, LI Tsansizi, TL Holmes… - Cell Reports, 2024 - cell.com
Summary Perlecan (HSPG2), a heparan sulfate proteoglycan similar to agrin, is key for
extracellular matrix (ECM) maturation and stabilization. Although crucial for cardiac …