Hunger & satiety signals: another key mechanism involved in the NAFLD pathway

I López-Méndez, ADC Maldonado-Rojas… - Frontiers in …, 2023 - frontiersin.org
Non-alcoholic fatty liver disease (NAFLD) is a highly prevalent metabolic disease, although
prevalence could change according to region, nowadays is considered a public health …

Recent Advances in the Synthesis of 3,4-Dihydropyran-2-Ones Organocatalyzed by N-Heterocyclic Carbenes

C Morales-Manrique, EA Baquero, J Guevara-Pulido - Molecules, 2023 - mdpi.com
In recent years, N-heterocyclic carbenes (NHC) have gained recognition as versatile
molecules capable of acting as organocatalysts in various reactions, particularly through the …

Cheminformatic Read-Across Approach Revealed Ultraviolet Filter Cinoxate as an Obesogenic Peroxisome Proliferator-Activated Receptor γ Agonist

S An, IG Park, SY Hwang, J Gong, Y Lee… - Chemical Research …, 2024 - ACS Publications
This study introduces a novel cheminformatic read-across approach designed to identify
potential environmental obesogens, substances capable of disrupting metabolism and …

Identification of Novel Organo-Se BTSA-Based Derivatives as Potent, Reversible, and Selective PPARγ Covalent Modulators for Antidiabetic Drug Discovery

F Chen, Q Liu, L Ma, C Yan, H Zhang… - Journal of Medicinal …, 2025 - ACS Publications
Recent studies have identified selective peroxisome proliferator-activated receptor γ
(PPARγ) modulators, which synergistically engage in the inhibition mechanism of PPARγ …

Alkaloids and Coumarins with Adiponectin-Secretion-Promoting Activities from the Leaves of Orixa japonica

P Nhoek, S Ahn, P Pel, YM Kim, J Huh… - Journal of Natural …, 2022 - ACS Publications
Fractionation of a methanol extract of Orixa japonica leaves led to the identification of five
new quinoline alkaloids (1, 2, 4, 8, and 9), three new coumarins (15, 17, and 19), and 20 …

Transcriptomics Demonstrates Significant Biological Effect of Growing Stem Cells on RGD-Cotton Scaffold

S Aouabdi, T Nedjadi, R Alsiary, F Mouffouk… - … Engineering Part A, 2024 - liebertpub.com
Stem cell therapy provides a viable alternative treatment for degenerated or damaged
tissue. Stem cells have been used either alone or in conjunction with an artificial scaffold …

Transcriptomic of mesenchymal stem cells growing on RGD conjugated cotton scaffold confers anti-aging, anti-inflammatory and osteogenesis potentials

S Aouabdi, T Nedjadi, R Alsiary, F Mouffouk, HR Ansari - 2023 - researchsquare.com
Background Stem cell therapy represents a good alternative therapy to the degenerated or
damaged tissue. Stem cells have been used solely or in combination with a scaffold. The …