ATP-binding cassette (ABC) superfamily comprises a large group of ubiquitous
transmembrane proteins that play a crucial role in transporting a diverse spectrum of …

Malaria still poses a major burden on human health around the world, especially in endemic
areas. Plasmodium resistance to several antimalarial drugs has been one of the major …

A limited number of antifungal drugs, the side-effect of clinical drugs and the emergence of
resistance create an urgent need for new antifungal treatment agents. High-throughput drug …

Candida glabrata is a prominent opportunistic fungal pathogen of humans. The increasing
incidence of C. glabrata infections is attributed to both innate and acquired resistance to …

This study aimed to assess the antifungal and antibiofilm efficacy of artemisinin against
Candida (C.) species, analyze its impact on gene expression levels within C. albicans …

Fungal infections and antifungal resistance are the increasing global public health concerns.
Mechanisms of fungal resistance include alterations in drug-target interactions …

The emergence of the pathogen Candida auris is a real concern worldwide, especially due
to its multidrug resistance profile, besides the difficulties in establishing the correct …

Recent studies have been indicating that many clinical drug combinations surpass single-
drug therapy efficacy. Machine learning, deep learning, network analysis, and search …

This study aimed to assess the antifungal and antibiofilm efficacy of artemisinin against
Candida (C.) species, analyze its impact on gene expression levels within C. albicans …

Introdução: A Candida auris tem se apresentado como um fungo altamente virulento e com
importante capacidade de resistência. É considerado um fungo emergente, oportunista e …